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ABSTRACT Five enzyme-linked immunosorbent assays developed to detect antibodies to different Burkholderia pseudomallei antigen preparations were evaluated as diagnostic tests for melioidosis in northeast Thailand. The highest diagnostic indices were observed for an affinity-purified antigen (sensitivity, 82%; specificity, 72%) and crude B. pseudomallei antigen (sensitivity, 81%; specificity, 70%), an improvement over the indirect hemagglutination assay (sensitivity, 73%; specificity, 64%).

Original publication

DOI

10.1128/cvi.00289-06

Type

Journal

Clinical and Vaccine Immunology

Publisher

American Society for Microbiology

Publication Date

01/2007

Volume

14

Pages

110 - 113