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This article reviews emerging Raman techniques for deep, non-invasive characterisation of biological tissues. As generic analytical tools, the new methods pave the way for a host of new applications including non-invasive bone disease diagnosis, chemical characterisation of 'stone-like' materials in urology and cancer detection in a number of organs.

Original publication

DOI

10.1039/b821100k

Type

Journal

The Analyst

Publication Date

06/2009

Volume

134

Pages

1058 - 1066

Addresses

Central Laser Facility, Science and Technology Facilities Council, Rutherford Appleton Laboratory, Harwell Science and Innovation Campus, Didcot, Oxfordshire, UK OX11 0QX. Pavel.Matousek@stfc.ac.uk

Keywords

Animals, Humans, Diagnostic Imaging, Tomography, Spectrum Analysis, Raman, Time Factors, Signal Processing, Computer-Assisted