{ "items": [ "\n\n
\n \n\n \n \n \n \n KWTRP\n \n \n \n \n NDM-CGHR\n \n \n\n \n\n\n
\n \n \n \nPosted 22/11/2023. Routine surveys are used to understand the training quality and experiences of junior doctors but there are lack of tools designed to evaluate the training experiences of interns in LMICs where working conditions and resource constraints are challenging. Yingxi Zhao and colleagues described their process developing and validating a \u201cmedical internship experience scale\u201d.
\n \n\n \n \n\n \n\n \n \n \n \n MORU\n \n \n \n \n OUCRU\n \n \n \n \n OUCRU-Nepal\n \n \n\n \n\n\n
\n \n \n \nPosted 17/11/2023. Early critical phase of the COVID-19 pandemic added tremendous pressure to find curative therapies. A lot of empirical treatments, including antimicrobials, were recommended. Drawing on interviews with patients, clinicians and drug dispensers, Bipin Adhikari and colleagues explore how and why antimicrobials may have been used for the management of COVID-19 in Nepal.
\n \n\n \n \n\n \n\n \n \n \n \n KWTRP\n \n \n \n \n NDM-CGHR\n \n \n\n \n\n\n
\n \n \n \nPosted 15/11/2023. Medical interns are an important workforce providing first-line healthcare services in hospitals. Yingxi Zhao and colleagues provided an overview of doctors\u2019 internship experience in Kenya and Uganda, and highlighted challenges experienced by interns spanning from burnout, stress, challenging working environment, inadequate support and poor quality of supervision.
\n \n\n \n \n\n \n\n \n \n \n \n MORU\n \n \n \n \n NDM-CGHR\n \n \n\n \n\n\n
\n \n \n \nPosted 10/22/2023. Sean Cavany and colleagues publish a new perspective in Nature Communications that describes the possible mechanisms by which substandard and falsified antimicrobials could affect antimicrobial resistance and suggests ways to improve our understanding of this relationship. The article arose from the work of the FORESFA project, funded by a Wellcome Collaborative Award.
\n \n\n \n \n\n \n\n \n \n \n \n KWTRP\n \n \n \n \n NDM-CGHR\n \n \n\n \n\n\n
\n \n \n \nPosted 07/11/2023. As COVID spread globally support for LMIC focused on skilled, technologically enabled ICU care. This ignored fundamental weaknesses in health systems and the need for basic, effective care to save lives in all clinical settings. Whole of system vigilance and response requires reorientation of priorities and effective change management, by Mike English.
\n \n\n \n \n\n \n\n \n \n \n \n COMRU\n \n \n \n \n LOMWRU\n \n \n \n \n MORU\n \n \n \n \n OUCRU\n \n \n \n \n OUCRU-Indonesia\n \n \n \n \n SMRU\n \n \n\n \n\n\n
\n \n \n \nPosted 01/11/2023. ACORN (A Clinically Oriented Antimicrobial Resistance Surveillance network) is a WHO GLASS compatible case-based surveillance method for antimicrobial resistance that produces more meaningful and locally actionable data. Rogier van Doorn and colleagues publish the results of a pilot in three countries, showing proof of principle and valuable lessons to be learned going forward. More at: acornamr.net
\n \n\n \n \n\n \n\n \n \n \n \n MORU\n \n \n\n \n\n\n
\n \n \n \nPosted 29/10/2023. Historically, vaccine mandates and opposition to vaccines have co-existed, starting with smallpox vaccination mandates in the 1800s. During the COVID-19 pandemic, the benefits of vaccine mandates were weighed against potential damage to public trust. Bipin Adhikari and colleagues discuss whether and how vaccine mandates can co-exist with public trust.
\n \n\n \n \n\n \n\n \n \n \n \n MORU\n \n \n\n \n\n\n
\n \n \n \nPosted 24/10/2023. In the review of a book \u2018Tore Godal and the evolution of global health by Conrad Keating\u2019, Bipin Adhikari and Lorenz von Seidlein discuss Tore Godal\u2019s contributions to Global Health projects while remaining in the background. There are lessons for those aspiring to influence Global Health.
\n \n\n \n \nApplications for 2023/24 are accepted from September 2022. For more information, visit the University\u2019s course pages for further details about the course and how to apply.
\n \n\n \n \n\n \n\n \n \n \n \n KWTRP\n \n \n\n \n\n\n
\n \n \n \nPosted 10/10/2023. Angela Moturi and colleagues evaluate RTS,S/AS01 malaria vaccine coverage in Kenya's pilot phase, showing high EPI (Extended Programme for Immunisation) user coverage (78%) for dose 3, but lower community coverage (57%). The 4th dose at 24 months had low coverage (<39%). Universal coverage of 3 doses of malaria vaccine needs improving. 24-month dosing remains a challenge.
\n \n\n \n \n\n \n\n \n \n \n \n KIMORU\n \n \n \n \n KWTRP\n \n \n \n \n MORU\n \n \n\n \n\n\n
\n \n \n \nPosted 29/09/2023. This large study on the pharmacokinetics of single low dose primaquine in young Ugandan and Congolese children will help the MORU team develop an optimal dose for children with falciparum malaria to block malaria transmission and contribute to malaria elimination, especially of resistant falciparum parasites. By Bob Taylor
\n \n\n \n \n\n \n\n \n \n \n \n KIMORU\n \n \n \n \n MORU\n \n \n \n \n SMRU\n \n \n\n \n\n\n
\n \n \n \nPosted 26/09/2023. In this pilot study, Caterina Fanello and colleagues evaluated the prevalence of neonatal hyperbilirubinemia and related neonatal and maternal risk factors in a semi-rural area of the Democratic Republic of Congo. They also explored knowledge and practices of expectant mothers regarding this condition. Ways forward to improve diagnosis and treatment in these settings are discussed.
\n \n\n \n \n\n \n\n \n \n \n \n MORU\n \n \n\n \n\n\n
\n \n \n \nPosted 22/09/2023. The transformation of village malaria workers (VMWs) into community health workers with roles beyond malaria is a promising approach for sustaining health care provision in remote areas. Rupam Tripura and colleagues discuss on how training on health education could be optimized for VMWs.
\n \n\n \n \n\n \n\n \n \n \n \n MORU\n \n \n\n \n\n\n
\n \n \n \nPosted 08/09/2023. Sharing results with participants from research studies is largely underappreciated. Bipin Adhikari and colleagues explore the perception and practice of results-sharing in malaria related clinical trials among researchers. Although there was a consensus on the rationale of result sharing to participants, most researchers thought that disseminating results to policymakers and stakeholders for research translation was more important.
\n \n\n \n \n\n \n\n \n \n \n \n MORU\n \n \n\n \n\n\n
\n \n \n \nPosted 06/09/2023. Sompob Saralamba and colleagues have proposed a new model explaining why increased dosing of antimalarial drug artemisinin doesn't speed up parasite clearance. It suggests that exposure to the drug makes some malaria parasites temporarily resistant, leading to either delayed death or reactivation. This could revolutionize treatment strategies for this deadly disease.
\n \n\n \n \n\n \n\n \n \n \n \n KWTRP\n \n \n \n \n MORU\n \n \n \n \n NDM-CGHR\n \n \n\n \n\n\n
\n \n \n \nPosted 30/08/2023. Alternative Design Trials (ADTs) and Adaptive Platform Trials (APTs) have enabled efficient large-scale testing of biomedical interventions during recent Public Health Emergencies (PHEs). Alun Davies and colleagues aimed to rapidly review evidence on engagement and informed consent for ADTs and APTs during PHE to consider what (if any) recommendations can inform practice.
\n \n\n \n \n\n \n\n \n \n \n \n MORU\n \n \n \n \n NDM-CGHR\n \n \n \n \n OUCRU\n \n \n \n \n SMRU\n \n \n\n \n\n\n
\n \n \n \nPosted 30/08/2023. This study by Makoto Saito and colleagues analysing 213 severe malaria cases in pregnancy at SMRU, MORU and OUCRU showed vital organ dysfunction led to high maternal and fetal mortality. In contrast, severe anaemia or hyperparasitaemia alone did not. This marked difference may explain the variation of mortality reported in the literature. Early diagnosis and treatment of malaria and anaemia in antenatal care should be promoted.
\n \n\n \n \n\n \n\n \n \n \n \n COMRU\n \n \n \n \n MORU\n \n \n\n \n\n\n
\n \n \n \nPosted 05/09/2023. Arjun Chandna and colleagues show that a point-of-care test for the soluble urokinase plasminogen activator receptor (suPAR) has good prognostic accuracy to predict oxygen requirement in patients presenting with moderate Covid-19 and suggest that suPAR should be explored for risk stratification of other infectious diseases.
\n \n\n \n \n\n \n\n \n \n \n \n OUCRU\n \n \n \n \n OUCRU-Indonesia\n \n \n\n \n\n\n
\n \n \n \nPosted 29/08/2023. A large-scale study in Indonesia found devastating consequences on TB control during the COVID-19 pandemic, estimating declines of TB case notification by 26% and treatment coverage by 11%. Districts with high COVID-19 incidence and limited healthcare resources were most affected. Henry Surendra, Raph Hamers and colleagues emphasise the need for resilient health systems.
\n \n\n \n \n