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\n \n\n \n9 November 2018
\n \n \n \nA systematic review analyses the results of 177 trials conducted between 1982 and 2016, including 18,436 patients who underwent electrocardiographic evaluation during malaria clinical trials. Nick White and colleagues found that serious cardiovascular side effects, which include sudden cardiac death, are very rare in the treatment of malaria with quinoline antimalarials. The work emphasises the importance of continued pharmacovigilance with the increasing use of quinoline antimalarials in mass treatment strategies such as intermittent preventative treatment and mass drug administration.
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\n \n\n \n7 November 2018
\n \n \n \nThe manufacture and distribution of medicines is a global industry, tainted by fake and substandard products. Not only might these drugs not work as expected, but some are even contributing to antimicrobial resistance. So, what\u2019s in your medicine cabinet? This is an article on Mosaic, a Wellcome publication
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\n \n\n \n4 September 2018
\n \n \n \nA team of researchers led by Yoel Lubell at MORU and IDDO used data from the USA and Thailand to link the consumption of antibiotics with the direct and indirect costs of treating patients for five drug-resistant bacterial infections.
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\n \n\n \n20 July 2018
\n \n \n \nA team of malaria experts from a large international research collaboration has today published results supporting the need for a radical cure strategy to tackle one of the most debilitating forms of malaria caused by the Plasmodium vivax parasite.
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\n \n\n \n13 June 2018
\n \n \n \nCurrent recommended treatment regimens for the most widely used medicine for uncomplicated Plasmodium falciparum malaria may be sub-optimal for small children and pregnant women according to a study led by Professor Joel Tarning.
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\n \n\n \n8 June 2018
\n \n \n \nOne of the world\u2019s most widely used anti-malarial drugs is safe to use, say researchers, after a thorough review and analysis of nearly 200,000 malaria patients who\u2019d taken the drug dihydroartemisinin-piperaquine (DHA-PPQ). There is such a low risk of sudden unexpected death from DHA-PPQ, one of the world\u2019s most effective medicines to treat malaria, that there is no need to limit its current use.
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\n \n\n \n25 May 2018
\n \n \n \nPrimaquine can be used to prevent the transmission of falciparum malaria from human to mosquito. Bob Taylor and colleagues at the Mahidol Oxford Research Unit (MORU) have developed an age-based regimen for single low-dose primaquine to block the transmission of malaria in sub-Saharan Africa.
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\n \n\n \n22 May 2018
\n \n \n \nIn a first of its kind study into the population and spread of tuberculosis-causing (TB) bacteria in Ho Chi Minh City, Thuong Thuong Nguyn and collegues at OUCRU Vietnam, Australia, UK and Singapore have found that more than half of cases can be attributed to one particular strain of the bacteria.
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\n \n\n \n11 May 2018
\n \n \n \nDr Marco J Haenssgen discusses the application of management thinking to solving the growing global problem of antimicrobial resistance.
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\n \n\n \n25 April 2018
\n \n \n \nThe rapid elimination of potentially untreatable P. falciparum malaria in South-East Asia is possible, according to a ground-breaking new study published today in The Lancet. The study authors say that setting up community-based malaria clinics for early diagnosis, treatment and monitoring, combined with mass antimalarial drug administration (MDA) to everyone living in \u2018hotspot\u2019 areas.
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\n \n\n \n10 April 2018
\n \n \n \nGiving paracetamol (acetaminophen) to patients ill with severe malaria made them less likely to develop potentially fatal kidney failure. Each year severe malaria causes close to half a million deaths globally. Acute kidney injury occurs in 40% of adults and at least 10% of children with severe malaria, killing an estimated 40% of these adults and 12-24% of the children. The study reported for the first time that giving regular doses of paracetamol protects the kidney in adult patients with severe falciparum malaria.
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\n \n\n \n27 March 2018
\n \n \n \nProfessor Kevin Baird, Head of EOCRU in Jakarta, Indonesia, talks about how more needs to be done to mitigate the threat of malaria in Asia Pacific. This article includes photos from Pearl Gan who travelled through the Asia Pacific region to capture the stories of people and communities impacted by malaria.
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\n \n\n \n9 March 2018
\n \n \n \nResearch led by Dr Marco Haenssgen has revealed how the complex cultural and social environment in developing countries can complicate the use of new diagnostic technologies to fight the global superbug crisis.
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\n \n\n \n6 March 2018
\n \n \n \nScience Blog. Professor Guy Thwaites, Director of the Oxford University Clinical Research Unit, Vietnam, explains the discovery of yet another use for one of the most ubiquitous and ancient of drugs \u2013 aspirin.
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\n \n\n \n9 February 2018
\n \n \n \nOver two-thirds of meat samples from Ho Chi Minh City were found to contain Salmonella bacteria, according to a study by the Oxford University Clinical Research Unit (OUCRU). Researchers purchased 117 samples of chicken meat, beef and pork from retail sites in 2016-2017; 68.4% of those samples were found to contain Salmonella bacteria.
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\n \n\n \n31 January 2018
\n \n \n \nTo fight the growing global threat of antibiotic-resistant bacteria, food labels around the world should include an \u2018antibiotic footprint\u2019 section that clearly shows the type and amount of antibiotics used to produce that food, say scientists in a study led by Associate Professor Direk Limmathurotsakul.
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\n \n\n \n23 January 2018
\n \n \n \nThe fast spread of mobile phones across low-income countries like India can make it harder for poorer people without phones to access essential health services, new research by Dr Marco Haenssgen suggests.
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\n \n\n \n21 September 2017
\n \n \n \nA highly drug resistant malaria \"superbug\" from western Cambodia is now present in southern Vietnam, leading to alarming failure rates for dihydroartemisinin (DHA)-piperaquine \u2014 Vietnam\u2019s national first-line malaria treatment, leading malaria scientists warn.
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\n \n\n \n21 August 2017
\n \n \n \nChanging home designs and materials to make homes cooler and harder for mosquitoes to enter could reduce malaria transmission in sub-Saharan Africa, according to a new study in The Lancet Planetary Health.
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\n \n\n \n1 August 2017
\n \n \n \nThe amount of influenza-specific antibodies present in an individual\u2019s blood can indicate not only if they experienced the flu, but potentially when - a finding that could improve disease monitoring in the tropics, where flu season is unending.\r\n\r\nIn the largest study of its kind, an international team, led by researchers from the Oxford University Clinical Research Unit in Ho Chi Minh City, Vietnam, the Erasmus Medical Centre in Rotterdam, Netherlands, and Penn State University, identified antibody concentrations that correspond to recent and past exposure to the flu strain H1N1 - the strain involved in the 2009 flu pandemic.
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