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\n \n\n \n26 July 2018
\n \n \n \nScientists are racing to stamp out the disease in Southeast Asia before unstoppable strains spread. This article features MORU, SMRU and colleagues, and explains what is happening and what we are doing to eliminate drug-resistant malaria in Southeast Asia before it spreads
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\n \n\n \n20 July 2018
\n \n \n \nA team of malaria experts from a large international research collaboration has today published results supporting the need for a radical cure strategy to tackle one of the most debilitating forms of malaria caused by the Plasmodium vivax parasite.
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\n \n\n \n19 June 2018
\n \n \n \nCollecting representative survey data on large populations of people can be a very time-consuming and expensive undertaking. But it doesn\u2019t have to be. Marco J. Haenssgen and Ern Charoenboon explain how they have used freely available satellite images to survey hard-to-reach communities in Thailand and Laos.
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\n \n\n \n13 June 2018
\n \n \n \nCurrent recommended treatment regimens for the most widely used medicine for uncomplicated Plasmodium falciparum malaria may be sub-optimal for small children and pregnant women according to a study led by Professor Joel Tarning.
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\n \n\n \n8 June 2018
\n \n \n \nOne of the world\u2019s most widely used anti-malarial drugs is safe to use, say researchers, after a thorough review and analysis of nearly 200,000 malaria patients who\u2019d taken the drug dihydroartemisinin-piperaquine (DHA-PPQ). There is such a low risk of sudden unexpected death from DHA-PPQ, one of the world\u2019s most effective medicines to treat malaria, that there is no need to limit its current use.
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\n \n\n \n30 May 2018
\n \n \n \nIn this Science Blog published on Oxford University website, Prof Paul Newton, Head of the Medicine Quality Group at the Infectious Diseases Data Observatory (IDDO) and the MORU Tropical Health Network and NDM Professor of Tropical Medicine i, explains the need for new strategies for tackling poor quality medical products.
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\n \n\n \n25 May 2018
\n \n \n \nPrimaquine can be used to prevent the transmission of falciparum malaria from human to mosquito. Bob Taylor and colleagues at the Mahidol Oxford Research Unit (MORU) have developed an age-based regimen for single low-dose primaquine to block the transmission of malaria in sub-Saharan Africa.
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\n \n\n \n22 May 2018
\n \n \n \nIn a first of its kind study into the population and spread of tuberculosis-causing (TB) bacteria in Ho Chi Minh City, Thuong Thuong Nguyn and collegues at OUCRU Vietnam, Australia, UK and Singapore have found that more than half of cases can be attributed to one particular strain of the bacteria.
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\n \n\n \n11 May 2018
\n \n \n \nDr Marco J Haenssgen discusses the application of management thinking to solving the growing global problem of antimicrobial resistance.
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\n \n\n \n25 April 2018
\n \n \n \nThe rapid elimination of potentially untreatable P. falciparum malaria in South-East Asia is possible, according to a ground-breaking new study published today in The Lancet. The study authors say that setting up community-based malaria clinics for early diagnosis, treatment and monitoring, combined with mass antimalarial drug administration (MDA) to everyone living in \u2018hotspot\u2019 areas.
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\n \n\n \n24 April 2018
\n \n \n \nAlmost one in four blood bank supplies in certain regions of Africa may have malaria parasites in them. UK scientists reviewed 26 studies that measured levels of Plasmodium parasites among blood donors in sub-Saharan Africa between 2000 and 2017. Percentages varied greatly across the nine countries included in the study, ranging from 0% to as much as 74%, with an average of 23.46% tested positive.
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\n \n\n \n20 April 2018
\n \n \n \n18 April 2018 (London) \u2013 The United Kingdom\u2019s Department for International Development (DFID) announced that it will commit \u00a39.2 million (USD 13.15 million) of research funding to DeTACT (Development of Triple Artemisinin Combination Therapies), a large multi-centre trial in 5 Asian and 10 African countries that aims to develop two new safe and effective malaria treatments using combinations of existing antimalarial drugs.
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\n \n\n \n17 April 2018
\n \n \n \nAs the second largest international donor, the UK has been at the forefront of efforts to reduce the number of cases for many years by investing in treatment, prevention and research, including the fight against the threat of drug resistance. The UK has announced further support for the fight against malaria to save more than 120,000 lives ahead of a Malaria Summit tomorrow with Commonwealth leaders.
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\n \n\n \n10 April 2018
\n \n \n \nPailin, a small settlement nestling in tropical rainforest near Cambodia\u2019s border with Thailand, lies at the heart of a region that has seen successive waves of resistance to malaria drugs arise in local people and then spread across the globe. As new waves of the disease threaten our health, worried scientists want to conduct a mass inoculation in a Cambodian region where new vaccines always seem to stop being effective.
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\n \n\n \n10 April 2018
\n \n \n \nGiving paracetamol (acetaminophen) to patients ill with severe malaria made them less likely to develop potentially fatal kidney failure. Each year severe malaria causes close to half a million deaths globally. Acute kidney injury occurs in 40% of adults and at least 10% of children with severe malaria, killing an estimated 40% of these adults and 12-24% of the children. The study reported for the first time that giving regular doses of paracetamol protects the kidney in adult patients with severe falciparum malaria.
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\n \n\n \n21 March 2018
\n \n \n \nTogether with Evidence Aid, Professor Jay Berkley from KWTRP is launching a process to get research into practice in humanitarian emergencies. Systematic reviews and teleconference meetings to discuss how clinical trials can inform programmes and practice are published online, with an editorial highlighting the issues and need for policies to be based on research evidence.
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\n \n\n \n16 March 2018
\n \n \n \nFIEBRE aims to design new evidence-based guidelines to manage fever, thereby ensuring that patients get drugs that give them the best chance of recovery, and thereby help stop the spread of antimicrobial resistance (AMR), a major global health problem.
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\n \n\n \n9 March 2018
\n \n \n \nResearch led by Dr Marco Haenssgen has revealed how the complex cultural and social environment in developing countries can complicate the use of new diagnostic technologies to fight the global superbug crisis.
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\n \n\n \n6 March 2018
\n \n \n \nScience Blog. Professor Guy Thwaites, Director of the Oxford University Clinical Research Unit, Vietnam, explains the discovery of yet another use for one of the most ubiquitous and ancient of drugs \u2013 aspirin.
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\n \n\n \n23 February 2018
\n \n \n \nMelioidosis is a bacterial infection that quietly causes thousands of deaths each year. Meet Direk Limmathurotsakul, the doctor who made it his mission to make the world take notice.
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