Elsevier

Vaccine

Volume 40, Issue 13, 18 March 2022, Pages 2011-2019
Vaccine

Unmet need for COVID-19 vaccination coverage in Kenya

https://doi.org/10.1016/j.vaccine.2022.02.035Get rights and content
Under a Creative Commons license
open access

Highlights

  • COVID-19 vaccination coverage was modelled using vaccination data from the Kenya Ministry of Health.

  • The average travel time to a designated COVID-19 vaccination site was a key predictor of COVID-19 vaccination coverage.

  • Bayesian modelling suggests inequalities in population vaccination coverage for COVID-19 at the sub-national level in Kenya.

  • Vaccination coverage mapping can be a useful tool for targeting interventions.

Abstract

COVID-19 has impacted the health and livelihoods of billions of people since it emerged in 2019. Vaccination for COVID-19 is a critical intervention that is being rolled out globally to end the pandemic. Understanding the spatial inequalities in vaccination coverage and access to vaccination centres is important for planning this intervention nationally. Here, COVID-19 vaccination data, representing the number of people given at least one dose of vaccine, a list of the approved vaccination sites, population data and ancillary GIS data were used to assess vaccination coverage, using Kenya as an example. Firstly, physical access was modelled using travel time to estimate the proportion of population within 1 hour of a vaccination site. Secondly, a Bayesian conditional autoregressive (CAR) model was used to estimate the COVID-19 vaccination coverage and the same framework used to forecast coverage rates for the first quarter of 2022. Nationally, the average travel time to a designated COVID-19 vaccination site (n = 622) was 75.5 min (Range: 62.9 – 94.5 min) and over 87% of the population >18 years reside within 1 hour to a vaccination site. The COVID-19 vaccination coverage in December 2021 was 16.70% (95% CI: 16.66 – 16.74) – 4.4 million people and was forecasted to be 30.75% (95% CI: 25.04 – 36.96) – 8.1 million people by the end of March 2022. Approximately 21 million adults were still unvaccinated in December 2021 and, in the absence of accelerated vaccine uptake, over 17.2 million adults may not be vaccinated by end March 2022 nationally. Our results highlight geographic inequalities at sub-national level and are important in targeting and improving vaccination coverage in hard-to-reach populations. Similar mapping efforts could help other countries identify and increase vaccination coverage for such populations.

Keywords

COVID-19
Vaccination coverage
Bayesian conditional autoregressive
Spatial inequalities

Abbreviations

CAR
Conditional Auto-regressive
COVAX
Coronavirus Disease of 2019 Vaccine Global Access facility
COVID-19
Coronavirus Disease of 2019
CPO
Condition Predictive Ordinate
CRA
Commission on Resource Allocation
DEM
Digital Elevation Model
DIC
Deviance Information Criterion
DTP
Diptheria-tetanus-pertussis
EUA
Emergency Use Authorization
FBO
Faith-Based Organization
GIS
Geographic Information System
INLA
Integrated Nested Laplace Approximation
KDHS
Kenya Demographic and Health Survey
KEPH
Kenya Essential Package for Health
MAE
Mean Absolute Error
MoH
Ministry of Health
NGO
Non-Governmental Organization
NPI
Non-Pharmaceutical Intervention
PBB
Pharmacy and Poisons Board
PIT
Probability Integral Transform
RCMRD
Regional Centre for Mapping of Resources for Development
RMSE
Root Mean Square Error
SAE
Small Area Estimation
SARS CoV-2
Severe Acute Respiratory Syndrome Coronavirus 2
WAIC
Watanabe-Akaike Information Criterion

Data availability statement

COVID-19 vaccination data are available with open access provided by the Ministry of Heath Kenya (https://www.health.go.ke/#1621663315215-d6245403-4901).

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