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The specificity and sensibility of IgM-IFAT for diagnosis of acute acquired and congenital toxoplasmosis may increase after separation of IgM fractions by simple gel filtration method. In the presence of IFA-IgG titers greater than 250 IU/ml with Remington test less than 1/50, specific IgM antibodies to Toxoplasma gondii should be detected by separation. The separation of IgM seems a necessary step for detecting IgM antibodies by IgM-IFA in the newborn sera.

Type

Journal

Bollettino dell'Istituto sieroterapico milanese

Publication Date

01/1984

Volume

63

Pages

453 - 457

Keywords

Humans, Toxoplasma, Toxoplasmosis, Toxoplasmosis, Congenital, Acute Disease, Immunoglobulin M, Antibodies, Fluorescent Antibody Technique, Chromatography, Gel, Adult, Infant, Newborn