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We determined complete viral genome sequences from three British healthcare workers infected with Ebola virus (EBOV) in Sierra Leone, directly from clinical samples. These sequences closely resemble those previously observed in the current Ebola virus disease outbreak in West Africa, with glycoprotein and polymerase genes showing the most sequence variation. Our data indicate that current PCR diagnostic assays remain suitable for detection of EBOV in this epidemic and provide confidence for their continued use in diagnosis.

Original publication





Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

Publication Date





Public Health England, Porton Down, Salisbury, United Kingdom.


Humans, Hemorrhagic Fever, Ebola, Sequence Analysis, Disease Outbreaks, Phylogeny, Genome, Viral, Travel, Health Personnel, Sierra Leone, Ebolavirus, Epidemics