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<jats:title>Abstract</jats:title> <jats:sec id="S0899823X2001243X_as1"> <jats:title>Background:</jats:title> <jats:p>Shortages of personal protective equipment during the coronavirus disease 2019 (COVID-19) pandemic have led to the extended use or reuse of single-use respirators and surgical masks by frontline healthcare workers. The evidence base underpinning such practices warrants examination.</jats:p> </jats:sec> <jats:sec id="S0899823X2001243X_as2"> <jats:title>Objectives:</jats:title> <jats:p>To synthesize current guidance and systematic review evidence on extended use, reuse, or reprocessing of single-use surgical masks or filtering face-piece respirators.</jats:p> </jats:sec> <jats:sec id="S0899823X2001243X_as3"> <jats:title>Data sources:</jats:title> <jats:p>We used the World Health Organization, the European Centre for Disease Prevention and Control, the US Centers for Disease Control and Prevention, and Public Health England websites to identify guidance. We used Medline, PubMed, Epistemonikos, Cochrane Database, and preprint servers for systematic reviews.</jats:p> </jats:sec> <jats:sec id="S0899823X2001243X_as4"> <jats:title>Methods:</jats:title> <jats:p>Two reviewers conducted screening and data extraction. The quality of included systematic reviews was appraised using AMSTAR-2. Findings were narratively synthesized.</jats:p> </jats:sec> <jats:sec id="S0899823X2001243X_as5"> <jats:title>Results:</jats:title> <jats:p>In total, 6 guidance documents were identified. Levels of detail and consistency across documents varied. They included 4 high-quality systematic reviews: 3 focused on reprocessing (decontamination) of N95 respirators and 1 focused on reprocessing of surgical masks. Vaporized hydrogen peroxide and ultraviolet germicidal irradiation were highlighted as the most promising reprocessing methods, but evidence on the relative efficacy and safety of different methods was limited. We found no well-established methods for reprocessing respirators at scale.</jats:p> </jats:sec> <jats:sec id="S0899823X2001243X_as6"> <jats:title>Conclusions:</jats:title> <jats:p>Evidence on the impact of extended use and reuse of surgical masks and respirators is limited, and gaps and inconsistencies exist in current guidance. Where extended use or reuse is being practiced, healthcare organizations should ensure that policies and systems are in place to ensure these practices are carried out safely and in line with available guidance.</jats:p> </jats:sec>

Original publication

DOI

10.1017/ice.2020.1243

Type

Journal

Infection Control & Hospital Epidemiology

Publisher

Cambridge University Press (CUP)

Publication Date

08/10/2020

Pages

1 - 9