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We conducted a genome-wide association study of male breast cancer comprising 823 cases and 2,795 controls of European ancestry, with validation in independent sample sets totaling 438 cases and 474 controls. A SNP in RAD51B at 14q24.1 was significantly associated with male breast cancer risk (P = 3.02 × 10 -13 ; odds ratio (OR) = 1.57). We also refine association at 16q12.1 to a SNP within TOX3 (P = 3.87 × 10 -15 ; OR = 1.50). © 2012 Nature America, Inc. All rights reserved.

Original publication

DOI

10.1038/ng.2417

Type

Journal

Nature Genetics

Publication Date

01/11/2012

Volume

44

Pages

1182 - 1184