Dr Joseph Donovan
Contact information
Research groups
Joseph Donovan
Senior Clinical Research Fellow
Dr Joseph Donovan is a clinical research physician based at OUCRU in Ho Chi Minh City. His primary research interest is in infectious diseases of the brain, particularly tuberculous meningitis.
Joseph is a Consultant in Infectious Diseases and General Internal Medicine (UK), and trained at centers including Imperial College London, University College London Hospitals NHS Trust, and the London School of Hygiene and Tropical Medicine. Joseph worked at OUCRU from 2017-2020 where he completed his PhD, and rejoined in 2025.
Meningitis and encephalitis lead to high rates of death and severe disability. Joseph is seeking new strategies to manage tuberculous meningitis, in addition to setting-appropriate techniques to optimize detection of critical illness, with the ultimate goal of improving patient outcomes from severe brain infection.
Recent publications
Genotype-stratified adjunctive dexamethasone for tuberculous meningitis in HIV-negative adults: a randomized controlled phase 3 trial
Journal article
Donovan J. et al, (2026), Nature Medicine, 32, 849 - 858
A clinical practice guideline for tuberculous meningitis.
Journal article
Donovan J. et al, (2026), The Lancet. Infectious diseases, 26, e96 - e111
Integrating metagenomic sequencing into diagnostic pathways for tuberculous meningitis - Authors' reply.
Journal article
Donovan J. et al, (2025), The Lancet. Infectious diseases, 25
Pre-treatment untargeted cerebrospinal fluid metabolomic profiling in tuberculous meningitis uncovers pathways associated with mortality.
Journal article
Le THN. et al, (2025), Med (New York, N.Y.), 6
Statistical analysis plan for the LAST ACT clinical trial; a Leukotriene A4 hydrolase Stratified non-inferiority Trial of Adjunctive Corticosteroids for HIV-negative adults with Tuberculous meningitis
Journal article
Donovan J. et al, (2025), Wellcome Open Research, 9, 695 - 695