Dr Philip Ashton
OUCRU Lead Bioinformatician
My primary research interest is the epidemiology of tuberculosis in Southeast Asia, specifically how Mycobacterium tuberculosis moves within and between; people, communities and countries. Currently the main tool I'm using to investigate this is whole genome sequencing (WGS), in combination with detailed epidemiological data. I'm also interested in various aspects of fungal pathogens, including genomic epidemiology and evolution of virulence in Cryptococcus neoformans and Talaromyces marneffei.
Three phylogenetic groups have driven the recent population expansion of Cryptococcus neoformans
Ashton PM. et al, (2019), Nature Communications, 10
Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues.
Meehan CJ. et al, (2019), Nature reviews. Microbiology, 17, 533 - 545
Epidemiological analysis of Salmonella clusters identified by whole genome sequencing, England and Wales 2014
Waldram A. et al, (2018), Food Microbiology, 71, 39 - 45
Whole genome sequencing reveals an outbreak of Salmonella Enteritidis associated with reptile feeder mice in the United Kingdom, 2012-2015
Kanagarajah S. et al, (2018), Food Microbiology, 71, 32 - 38
Public health surveillance in the UK revolutionises our understanding of the invasive Salmonella Typhimurium epidemic in Africa
Ashton PM. et al, (2017), Genome Medicine, 9