Dr Xin Hui S Chan
Xin Hui Chan
BMBCh MA MSc DPhil MRCP DTM&H
Big data for malaria elimination
Dr Xin Hui Chan is a clinical investigator at the Mahidol-Oxford Tropical Medicine Research Unit (MORU) and specialty registrar in infectious diseases and general internal medicine at the London Hospital for Tropical Diseases. She was a member of the University of Oxford-MRC Doctoral Training Partnership, a recipient of the University of Oxford NDM Doctoral Prize Studentship, and lecturer in medicine at Worcester College, University of Oxford.
Xin Hui is interested in translating scientific research into actionable interventions. Her current research focuses on optimising interventions for malaria elimination and containment of antimalarial resistance through evidence synthesis and clinical investigation. Her work combines drug safety / pharmacovigilance, pharmacoepidemiology, clinical pharmacology, and genomic epidemiology studies. She was the WHO technical resource person and rapporteur of the WHO Evidence Review Group on the Cardiotoxicity of Antimalarial Medicines.
Xin Hui's previous experience has been with the University of Oxford, the London School of Hygiene and Tropical Medicine, the MRC Unit in The Gambia, the US National Institutes of Health, and the UK Faculty of Medical Leadership and Management. She holds postgraduate qualifications in internal medicine, infectious diseases, and tropical medicine.
Barriers and facilitators to healthcare workers’ adherence with infection prevention and control (IPC) guidelines for respiratory infectious diseases: a rapid qualitative evidence synthesis
Houghton C. et al, (2020), Cochrane Database of Systematic Reviews
Factors affecting the electrocardiographic QT interval in malaria: A systematic review and meta-analysis of individual patient data
Chan XHS. et al, (2020), PLOS Medicine, 17, e1003040 - e1003040
A Temporizing Solution to “Artemisinin Resistance”
(2019), New England Journal of Medicine, 381, 989 - 990
Evolution and expansion of multidrug-resistant malaria in southeast Asia: a genomic epidemiology study
Hamilton WL. et al, (2019), The Lancet Infectious Diseases, 19, 943 - 951
The impact of targeted malaria elimination with mass drug administrations on falciparum malaria in Southeast Asia: A cluster randomised trial
von Seidlein L. et al, (2019), PLOS Medicine, 16, e1002745 - e1002745
The arrhythmogenic cardiotoxicity of the quinoline and structurally related antimalarial drugs: a systematic review
Haeusler IL. et al, (2018), BMC Medicine, 16
Risk of sudden unexplained death after use of dihydroartemisinin–piperaquine for malaria: a systematic review and Bayesian meta-analysis
Chan XHS. et al, (2018), The Lancet Infectious Diseases, 18, 913 - 923
Zinc supplementation for preventing mortality, morbidity, and growth failure in children aged 6 months to 12 years of age
Mayo-Wilson E. et al, (2014), Cochrane Database of Systematic Reviews
A QuESt for speed: rapid qualitative evidence syntheses as a response to the COVID-19 pandemic
Biesty L. et al, (2020), Systematic Reviews, 9
Extended use or re-use of single-use surgical masks and filtering facepiece respirators during COVID-19: A rapid systematic review.
Toomey E. et al, (2020), Infection control and hospital epidemiology, 1 - 25