Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Accept all cookies Reject all non-essential cookies Find out more

Positive serological tests for syphilis and administration of intravenous immunoglobulin.

Constable SA., Parry CM., Enevoldson TP., Bradley M.

We report the case of a man who tested positive for syphilis following the intravenous administration of human normal immunoglobulin as part of the treatment of Guillain-Barré syndrome. The chronology of the testing suggested the passive acquisition of treponemal antibody. This phenomenon is not widely documented in the medical literature, but is a theoretical risk of treatment, and serves as a reminder to be cautious in the interpretation of such serological tests.

More information Original publication

DOI

10.1136/sti.2006.020503

Type

Journal article

Publication Date

2007-02-01T00:00:00+00:00

Volume

83

Pages

57 - 58

Total pages

1

Addresses

D, e, p, a, r, t, m, e, n, t, , o, f, , P, h, a, r, m, a, c, o, l, o, g, y, , a, n, d, , T, h, e, r, a, p, e, u, t, i, c, s, ,, , U, n, i, v, e, r, s, i, t, y, , o, f, , L, i, v, e, r, p, o, o, l, ,, , A, s, h, t, o, n, , S, t, r, e, e, t, , M, e, d, i, c, a, l, , S, c, h, o, o, l, ,, , A, s, h, t, o, n, , S, t, r, e, e, t, ,, , L, i, v, e, r, p, o, o, l, , L, 6, 9, , 3, G, E, ,, , U, K, ., , s, ., c, o, n, s, t, a, b, l, e, @, l, i, v, e, r, p, o, o, l, ., a, c, ., u, k

Keywords

Humans, Treponema pallidum, Syphilis, Guillain-Barre Syndrome, Immunoglobulins, Intravenous, Antibodies, Bacterial, False Positive Reactions, Syphilis Serodiagnosis, Sensitivity and Specificity, Adult, Male