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Identifying fake Covid-19 vaccines by analysing vial labels and vaccine liquids

Researchers at the Medicine Quality Research Group, University of Oxford and collaborators, including the Serum Institute of India, have published an innovative method to identify falsified vaccines without opening the vaccine vial.

Blog: Research priorities for a warming world

Professor Deirdre Hollingsworth, Professor of Infectious Disease Epidemiology at NDM’s Centre for Tropical Medicine and Global Health and the Big Data Institute, looks at potential ways to advance research on the impact of climate change on malaria and neglected tropical diseases (NTDs).

Oxford tops THE subject ranking in medicine for 14th consecutive year

The University of Oxford has once again been named the top institution in the Times Higher Education (THE) Subject Rankings for Clinical, Pre-Clinical, and Health, marking an impressive 14th consecutive year in this prestigious position.

The Global Health Network reaches 1 million members

The Global Health Network has achieved a remarkable milestone: one million members worldwide. This dynamic and inclusive community of healthcare professionals and researchers is addressing two of the most pressing challenges in global health. By equipping teams to tackle everyday diseases of poverty and strengthening the ability to detect and respond to emerging threats, The Global Health Network is saving lives and safeguarding the future of global health.

Myanmar-Thailand: Healthcare access without barriers

In Myanmar, the United Nations reports that 3 million people have been displaced due to the ongoing civil war. The 2021 coup intensified conflicts and worsened the humanitarian crisis, forcing at least a hundred thousand to seek refuge and medical care in Thailand. The Tak province, a key crossing point between the two countries, sees a rising number of new migrants (with 40% of women) crossing the border every day. In response to this health emergency caused by these large-scale forced displacements, the SMRU and M-FUND projects have concentrated their efforts along the border area.

New Hospital Networks for Antimicrobial Stewardship in Vietnam

OUCRU Ha Noi and the National Hospital for Tropical Diseases (NHTD), under the guidance of the Department of Health, are collaborating to establish local hospital networks for Antimicrobial Stewardship (AMS) across Vietnam. This initiative, connecting district hospitals with provincial hospitals, leverages existing systems and resources to enhance AMS implementation and strengthen efforts against antimicrobial resistance (AMR).

56.8% of Young People Lost Concentration or Interest in Living in 2021

High numbers of mental health issues in children and adolescents highlight the urgent need for a systematic approach to young people’s mental health and the importance of developing support systems at home, in schools, and throughout society. OUCRU Collab Lab‘s mission is to make health science, including mental health, research more accessible and relatable to young people, and university students are their main target audience and stakeholders.

Launch of largest-ever study tracking chikungunya burden in East Africa

A team of scientists in the UK, Kenya and Tanzania will soon find out the extent to which chikungunya, a debilitating mosquito-borne disease causing large outbreaks in Asia and South America, is also affecting countries in East Africa.

OUCRU workshop bridges research and clinical practice on Pneumococcal infections

On November 22, 2024, the Zoonoses research group at OUCRU, in collaboration with Children's Hospital 2, Ho Chi Minh City, successfully organised a scientific workshop: "Community-acquired pneumonia: Update on pneumococcal infection with vaccines, drug resistance and multiple infections". The workshop attracted nearly 70 experts, including doctors, nurses, medical students, and technicians.

AMR booklet by Shuma Banik

IHTM alumna, Shuma Banik, has written and painted a booklet about the growing problem of antimicrobial resistance (AMR) in Assam, India.

Oxford Clinical Lecturer awarded prestigious BIA Barnet Christie Lecture

Xin Hui Chan has won the competitive 2024 Barnet Christie Lecture award of the British Infection Association. As part of the award, Dr Chan delivered a lecture entitled ‘Drugs for Tropical Infections: Challenges, Opportunities, and the Infectious Disease Physician’

KEMRI renews collaboration with Oxford University and Wellcome Trust

The Kenya Medical Research Institute (KEMRI) has signed a seven-year memorandum of agreement with the Wellcome Trust and the University of Oxford. Under this collaboration, Wellcome has awarded £91 million (KES 15 billion) to support research over the next seven years. KEMRI have been collaborating with the Wellcome Trust and the University of Oxford on improving health through research for over 35 years.

Study finds methaemoglobin levels could predict malaria recurrence

A new study has found methaemoglobin levels during treatment for vivax malaria could be used to predict whether a patient would have recurrent malaria.

OUCRU researchers help shape global priorities in AMR research

OUCRU researchers from Indonesia, Nepal, and Vietnam contributed to the newly published WHO research priorities for AMR. These top 40 priorities, developed by the World Health Organization (WHO) with global collaborators, aim to guide research into drug-resistant infections over the next five years, with a special focus on challenges faced by low- and middle-income countries (LMICs).

The Important Role of Young People in Tackling AMR

Antimicrobial resistance (AMR) is a growing global health and socioeconomic crisis. Regardless of its impact on human and animal health, food production, and the environment that could happen to everyone, everywhere, there’s still much to be done to raise public and stakeholder awareness. A global online survey of nearly 200 stakeholders from human, animal, plant, and environmental health sectors also highlighted the need for increased public awareness and action.

Improving antimicrobial resistance control in resource-limited areas: A success story from Phu Tho, Vietnam

OUCRU and the Phu Tho Department of Health have partnered to improve antibiotic stewardship and microbiology capabilities in underserved districts of the province. A recent semi-final meeting was held to review the project's progress and celebrate its achievements.

Dialogue drama on adolescent pregnancy in a marginalised migrant population on the Thailand-Myanmar border

A participatory-action approach involving community members and adolescents resulted in a dialogue-drama on adolescent pregnancy, contraception, and choice in the event of an unplanned pregnancy. The dialogue-drama augmented discussion of traditionally taboo issues and this ethnographic method is potentially useful for similar global health settings.

Indonesia faces gaps in hospital antibiotic programmes amid fight against antimicrobial resistance, study by Universitas Indonesia and OUCRU Indonesia finds

A nationwide study led by Faculty of Medicine Universitas Indonesia (FMUI) and OUCRU Indonesia found that 9 out of 10 hospitals in a sample of 575 across 34 provinces of Indonesia had a formal Antimicrobial Stewardship Programme. But only half of those had reached a development level where they could run a robust, functional stewardship programme.

MODRA Workshop 2: Putting research ideas into action

The MORU-OUCRU Discovery Research Academy (MODRA) Workshop 2 was recently held in Ho Chi Minh City, Vietnam.

OUCRU hosts BactiVac Network Meeting to drive global vaccine development

The 5th Annual BactiVac Network Meeting, co-hosted by the Oxford University Clinical Research Unit (OUCRU) and the Bacterial Vaccines Network, took place from 4-7 November 2024 in Ho Chi Minh City, Vietnam.

Applying genetic technology for early tuberculous meningitis diagnosis helps enhance patients’ quality of life

Vietnam remains a country with a high tuberculosis burden, with tuberculous meningitis (TBM) being particularly challenging to detect early, often leading to severe neurological sequelae in patients. With the mission of addressing global health issues, Collab Lab, an initiative led by OUCRU’s Public and Community Engagement group, has chosen to animate a publication about TBM, aims to raise awareness about tuberculosis in general, TBM, and the importance of BCG vaccination for children.

The Medicine Quality Research Group invited to present at the World Health Summit, Berlin, 15th October

Dr Gesa Gnegel and Dr Céline Caillet were invited to present their current work during a session at the World Health Summit. This international forum and leading global health conference brings together stakeholders from politics, science, the private sector, and civil society. The aim of this event that took place in Berlin from the 13th to the 15th of October 2024 is ‘to set the agenda for a healthier future by inspiring innovative solutions for better health and well-being for all’.

Caesar Atuire interview

Dr Caesar Atuire was recently interviewed for an article in Science on 29 October 2024 on the renewed version of the declaration of Helsinki.

New Research Sheds Light on Deadly TB Meningitis: Finding cues in the blood

In a new study published in eLife Journal, OUCRU researchers identified gene activity signatures in the blood of patients with a life-threatening form of tuberculosis.

Dengue: Are Baby Mosquitoes a Hidden Threat?

Did you know that dengue fever cases have witnessed a ten-fold surge in the past two decades? This tropical disease continues to be a global health situation. The fight against dengue has become increasingly complicated due to drastic changes in mosquito behavior and geographical distribution. Traditionally, we’ve focused on preventing mosquito bites. But now, researchers are asking a crucial question: What happens when the dengue virus passes from mosquito to mosquito? Through vertical transmission - where a mother mosquito passes the virus to her offspring - could baby mosquitoes also spread dengue? If so, we’re facing a new threat and have to develop new strategies against this new enemy, baby mosquitos!

Innovative diagnostics, new tools, near-elimination strategies, cross-border collaborations top agenda at malaria elimination joint meeting

From 24-26 Sept, the Asia Pacific Malaria Elimination Network (APMEN) Vivax Working Group (VxWG) and Surveillance & Response Working Group (SRWG) held their 2024 Joint Annual Meeting in Kuching, Malaysia. Co-organized by SRWG and VxWG host institutions MORU and Medicines for Malaria Venture (MMV), the event took place immediately following the 2024 International Congress for Tropical Medicine and Malaria (ICTMM).

Dr Claire Chewapreecha wins Nature Award for Inspiring Women in Science

Dr Chewapreecha, a Wellcome International Intermediate Fellow and computational biologist at NDM's Mahidol-Oxford Tropical Medicine Research Unit, has been announced as the Individual Winner at this year’s Inspiring Women in Science Awards hosted by Nature and The Estée Lauder Companies. She was honoured at a ceremony in London on 31 October.

Experts gather to discuss medicine quality research

Experts from across Europe joined forces to discuss research on substandard and falsified medical products and how to translate the evidence into policy and implementation. Over forty participants from various countries around the world, all based in Europe, including the UK, Sweden, France, Germany and Belgium, joined the in-person informal event at the Richard Doll Building, in Oxford, on the 24th of October.

Lorenz von Seidlein awarded RSTMH medal for outstanding work in tropical health

On 10 Oct in London, the Royal Society for Tropical Medicine and Hygiene (RSTMH) awarded MORU’s Prof Lorenz von Seidlein (centre) the Donald Mackay Medal for outstanding work in tropical health, especially relating to improvements in the health of rural or urban workers in the tropics.

Forum Theatre: Exploring Community’s Power and Raising Awareness

Forum Theatre, a branch of the so-called Theatre of the Oppressed, is an interactive and participatory form of theatre developed by Brazilian theatre practitioner Augusto Boal in the 1970s. This unique approach has the potential to explore a community’s voice and raise awareness by empowering people with a tool that encourages them to change reality through their own suggestions for real social issues.

The Global Health Network MENA Regional Hub officially launched

The Global Health Network, hosted by NDM-CGHR, proudly announced the official launch of its Middle East North Africa (MENA) Regional Hub, an initiative set to revolutionise health research, education, and practice across the region. The launch event was held at the Canadian University Dubai on the 21st October 2024, and brought together leading experts, policymakers, and academic institutions to chart a path toward a healthier and more resilient future for the MENA region.

Wellcome Trust Delegates Visit OUCRU Indonesia

On 14 October 2024, a delegation from Wellcome visited OUCRU Indonesia to deepen their understanding of the unit’s research, learn about its collaborations with various partners, and gain insights into its capacity-building initiatives for local researchers.

MoU University of Oxford and the University of Seychelles

IHTM Course Director, Proochista Ariana, travelled to Seychelles in October to sign a Memorandum of Understanding, MoU, between the University of Oxford and the University of Seychelles, with the focus on research, education and evidenced-based policymaking.

Rift Valley fever vaccine to enter Phase II clinical trials in Kenya

A promising human vaccine candidate against the potentially deadly Rift Valley fever, a mosquito-borne disease affecting countries across Africa, is set to begin Phase II trials in Kenya. This is the most advanced stage of testing a human Rift Valley fever vaccine has reached in an outbreak-prone area to date. A team of scientists at the Nuffield Department of Medicine and the KEMRI-Wellcome Trust Research Programme will lead the $3.7m trial, funded by the Coalition for Epidemic Preparedness Innovations (CEPI).

It’s time to prioritise mental health at workplace

10th October is World Mental Health Day. This year’s official theme, “It’s Time to Prioritise Mental Health in the Workplace,” once again emphasised the importance of mental health in professional settings. The global campaign aimed to advocate for improved mental healthcare systems and procedures in workplaces, ensuring employees feel their mental health is prioritised, protected, and promoted.

AMR surveillance challenges

Dr Geetanjali Kapoor gives a series of talks on AMR surveillance best practices 9-15 October, understanding real-world challenges associated with large datasets from disparate sources, laboratory methods, country workshops, and the importance of AMR surveillance. The series is based on her experiences as a Fleming Fund regional grantee in Africa.

Blog: End of life care in Vietnam

Luu Phuoc An, a PhD student at NDM’s Oxford University Clinical Research Unit (OUCRU), is dedicated to improving end of life care in Vietnam. Her research explores the complex cultural, emotional, and medical aspects of death and dying in hospital settings.

IHTM 10 years on

IHTM is celebrating reaching its first decade and is delighted to welcome the tenth cohort of inspiring individuals to the University of Oxford.

MODRA Workshop Empowers Early-Career Scientists to Secure Competitive Research Grants

The MORU-OUCRU Discovery Research Academy (MODRA) recently concluded its inaugural workshop in Bangkok. This intensive five-day programme equipped 15 promising postdoctoral researchers with the skills required to complete a high-quality seed proposal.

New study to support WHO guideline changes

A new study which will help inform World Health Organization guidelines for treating children with Plasmodium vivax malaria has found that giving children higher doses of primaquine substantially reduced recurrences of malaria.

Youth Ambassadors Aim to Raise Tetanus Awareness Through Public and Community Engagement Activities

OUCRU Youth Science Ambassadors (YSA) project, launched in 2021, has become a key youth engagement activities of OUCRU’s Public and Community Engagement Group. Becoming part of the project, young participants are empowered to lead, propose, plan, and execute their own initiatives addressing specific issues they identify themselves.

New Study Shows High Acceptability for Point-of-Care Testing to Improve Antibiotic Use in Vietnam

OUCRU Hanoi’s new study has found high levels of acceptability for a point-of-care testing service to improve antibiotic dispensing for respiratory infections in Vietnamese pharmacies.

FORESFA collaborators meet for third annual project update

Collaborators of a multi-country project aimed at better understanding the impact, origin and trade routes of falsified medical products gathered to share updates and make final year plans.

Improving survival rates of children with sickle cell disease in Kenya

Research on sickle cell disease conducted by KEMRI-Wellcome Trust Research Programme (KWTRP) at the Nuffield Department of Medicine shows significant progress in understanding how to improve survival rates and quality of life for those living with the condition.

Central Ho Chi Minh City identified as a hotspot for tuberculosis

A recent study identified key factors contributing to the tuberculosis burden in Ho Chi Minh City, conducted by researchers from the Oxford University Clinical Research Unit in Vietnam (OUCRU) and Pham Ngoc Thach Hospital.

Professor English hosts Workshop on Patient Safety in Low-Resource Hospitals

Last week Professor Mike English led a workshop at the Christ Church Research Centre focused on Patient Safety in Low-Resource Setting Hospitals. The event is part of a broader initiative aimed at developing practical solutions for improving patient safety in healthcare environments with limited resources.

Antibiotic resistance has claimed at least one million lives each year since 1990: GRAM

Landmark GRAM Project study of global AMR burden over time forecasts a sharp rise in deaths, with 39 million lives lost between now and 2050

Hydroxychloroquine provides moderate COVID-19 prevention, large clinical trial shows

Four years after being derailed by scientific fraud and politicised science in the first year of the pandemic, COPCOV, the world’s largest COVID-19 chemoprevention study, finally published results today that showed that hydroxychloroquine (HCQ) does have a moderate benefit in preventing COVID-19.

KWTRP exhibits at the Kenya National Research Festival 2024

KEMRI-Wellcome Trust Research Programme (KWTRP) hosted an exhibition as part of the British High Commission Pavilion during the Kenya National Research Festival 2024. Under the theme “Research Partnerships and collaborations for Socio-Economic Transformation” the festival aimed to raise awareness about the diverse spectrum of research activities in Kenya and internationally encouraging collaboration.

Seven CTMGH researchers awarded full professorships

We are delighted to announce that seven of our researchers have been awarded the title of Professor, in recognition of their research achievements, contribution to teaching, and contribution to the general work of the Nuffield Department of Medicine.

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