26 July 2018
Scientists are racing to stamp out the disease in Southeast Asia before unstoppable strains spread. This article features MORU, SMRU and colleagues, and explains what is happening and what we are doing to eliminate drug-resistant malaria in Southeast Asia before it spreads
20 July 2018
A team of malaria experts from a large international research collaboration has today published results supporting the need for a radical cure strategy to tackle one of the most debilitating forms of malaria caused by the Plasmodium vivax parasite.
10 July 2018
KWTRP Community Liaison Group is working with the Jukwaa Arts Productions using a magnet theatre model to sensitize the communities/publics within Kilifi County about the Research work undertaken at the programme, and to learn about community/public concerns.
3 July 2018
The Infectious Disease Data Observatory and The Global Health Network have signed a Wellcome joint statement, along with the Gates Foundation, Lancet, PLOS and others, to help ensure data on the current Ebola outbreak in the Democratic Republic of Congo is free to access and shared rapidly.
27 June 2018
Lessons learned from past Ebola epidemics are helping to combat a fresh outbreak in the Democratic Republic of Congo (DRC). Investing in new vaccines, diagnostic tests and laboratories is paying off as expert networks spring into action.
19 June 2018
ASTMH nominated Professor Rose McGready, SMRU Deputy Director, as an Honorary International Fellow. Rose received the prestigious award in recognition of outstanding accomplishment by an “individual not an American citizen who has made eminent contributions to some phase of tropical medicine and hygiene”. Rose will formally receive her award at the ASTMH Annual Meeting, to be help 28 Oct-1 Nov in New Orleans, Louisiana.
19 June 2018
Collecting representative survey data on large populations of people can be a very time-consuming and expensive undertaking. But it doesn’t have to be. Marco J. Haenssgen and Ern Charoenboon explain how they have used freely available satellite images to survey hard-to-reach communities in Thailand and Laos.
15 June 2018
The proliferation of poor quality medical products is an important but neglected public health problem, threatening millions of people all over the world, both in developing and wealthy countries. A pioneering conference will bring leading professionals from all over the world to Oxford, September 23-28, to discuss strategies for tackling poor quality medical products on a global scale.
13 June 2018
Current recommended treatment regimens for the most widely used medicine for uncomplicated Plasmodium falciparum malaria may be sub-optimal for small children and pregnant women according to a study led by Professor Joel Tarning.
8 June 2018
One of the world’s most widely used anti-malarial drugs is safe to use, say researchers, after a thorough review and analysis of nearly 200,000 malaria patients who’d taken the drug dihydroartemisinin-piperaquine (DHA-PPQ). There is such a low risk of sudden unexpected death from DHA-PPQ, one of the world’s most effective medicines to treat malaria, that there is no need to limit its current use.
30 May 2018
In this Science Blog published on Oxford University website, Prof Paul Newton, Head of the Medicine Quality Group at the Infectious Diseases Data Observatory (IDDO) and the MORU Tropical Health Network and NDM Professor of Tropical Medicine i, explains the need for new strategies for tackling poor quality medical products.
25 May 2018
Primaquine can be used to prevent the transmission of falciparum malaria from human to mosquito. Bob Taylor and colleagues at the Mahidol Oxford Research Unit (MORU) have developed an age-based regimen for single low-dose primaquine to block the transmission of malaria in sub-Saharan Africa.
23 May 2018
The first-ever dedicated academic conference to discuss Medicine Quality & Public Health bringing together people from a diversity of sectors: public health, national regulatory authority, pharmacy, biomedical, chemistry, law, ethics, cultural and social sciences, the pharmaceutical industry, international organisations, NGOs, national procurement centres, also scientists working on internet and pharmaceutical forensics. 23rd-28th September 2018 at Keble College, Oxford. Submit your abstract by 1 June 2018
22 May 2018
In a first of its kind study into the population and spread of tuberculosis-causing (TB) bacteria in Ho Chi Minh City, Thuong Thuong Nguyn and collegues at OUCRU Vietnam, Australia, UK and Singapore have found that more than half of cases can be attributed to one particular strain of the bacteria.
22 May 2018
On 10 May 2018, SMRU Deputy Director Rose McGready was awarded the Alumni Award for Service to Humanity by the University of Sydney. The Alumni Award recognizes the personal contribution of alumni who, through service to philanthropy, improve the lives of those in need. It also seeks to recognize the significant involvement of Sydney alumni in projects that enrich local or international communities.
11 May 2018
Dr Marco J Haenssgen discusses the application of management thinking to solving the growing global problem of antimicrobial resistance.
11 May 2018
Seven Oxford scientists are amongst 48 of the UK's world-leading researchers elected to join the prestigious Fellowship of the Academy of Medical Sciences this year. Fellows are elected for their outstanding contributions to biomedical and health science, leading research discoveries, and translating developments into benefits for patients and the wider society.
9 May 2018
The Royal Society recognises Professor Dominic Kwiatkowski’s pioneering work on malaria, and particularly the use of genomic epidemiology to understand the evolutionary arms race that is going on between human, parasite and mosquito populations in Africa and other tropical regions of the world. Professor Kwiatkowski joins an existing membership of approximately 1600 of the most distinguished scientists from the United Kingdom, other Commonwealth countries and the Republic of Ireland.
25 April 2018
The rapid elimination of potentially untreatable P. falciparum malaria in South-East Asia is possible, according to a ground-breaking new study published today in The Lancet. The study authors say that setting up community-based malaria clinics for early diagnosis, treatment and monitoring, combined with mass antimalarial drug administration (MDA) to everyone living in ‘hotspot’ areas.
24 April 2018
While many LMICs still lack appropriate access to antibiotics, a global increase is driven largely by some developing countries which face more drug-resistant infections. To tackle antimicrobial resistance, we need to look at all the factors behind how and when antibiotics are used. A common obstacle is lack of access to clean water, which makes preventing and controlling infections nearly impossible.
24 April 2018
Almost one in four blood bank supplies in certain regions of Africa may have malaria parasites in them. UK scientists reviewed 26 studies that measured levels of Plasmodium parasites among blood donors in sub-Saharan Africa between 2000 and 2017. Percentages varied greatly across the nine countries included in the study, ranging from 0% to as much as 74%, with an average of 23.46% tested positive.
20 April 2018
ITV News has travelled across the world to report on the growing global threat of the spread of deadly drug-resistant 'super bugs'. In the first of their three-part series, they investigate the frontline fight against deadly malaria parasites in South East Asia threatening a new global emergency.
20 April 2018
18 April 2018 (London) – The United Kingdom’s Department for International Development (DFID) announced that it will commit £9.2 million (USD 13.15 million) of research funding to DeTACT (Development of Triple Artemisinin Combination Therapies), a large multi-centre trial in 5 Asian and 10 African countries that aims to develop two new safe and effective malaria treatments using combinations of existing antimalarial drugs.
18 April 2018
Investments worth more than £2.7bn are being pledged today in a drive to halve the number of malaria cases across the Commonwealth. Heads of state and business leaders are convening in London to galvanise the fight against the disease, which has seen a resurgence in some areas.
17 April 2018
As the second largest international donor, the UK has been at the forefront of efforts to reduce the number of cases for many years by investing in treatment, prevention and research, including the fight against the threat of drug resistance. The UK has announced further support for the fight against malaria to save more than 120,000 lives ahead of a Malaria Summit tomorrow with Commonwealth leaders.
10 April 2018
Pailin, a small settlement nestling in tropical rainforest near Cambodia’s border with Thailand, lies at the heart of a region that has seen successive waves of resistance to malaria drugs arise in local people and then spread across the globe. As new waves of the disease threaten our health, worried scientists want to conduct a mass inoculation in a Cambodian region where new vaccines always seem to stop being effective.
10 April 2018
Giving paracetamol (acetaminophen) to patients ill with severe malaria made them less likely to develop potentially fatal kidney failure. Each year severe malaria causes close to half a million deaths globally. Acute kidney injury occurs in 40% of adults and at least 10% of children with severe malaria, killing an estimated 40% of these adults and 12-24% of the children. The study reported for the first time that giving regular doses of paracetamol protects the kidney in adult patients with severe falciparum malaria.
27 March 2018
Professor Kevin Baird, Head of EOCRU in Jakarta, Indonesia, talks about how more needs to be done to mitigate the threat of malaria in Asia Pacific. This article (p. 11 onwards) includes photos from Pearl Gan who travelled through the Asia Pacific region to capture the stories of people and communities impacted by malaria.
21 March 2018
Together with Evidence Aid, Professor Jay Berkley from KWTRP is launching a process to get research into practice in humanitarian emergencies. Systematic reviews and teleconference meetings to discuss how clinical trials can inform programmes and practice are published online, with an editorial highlighting the issues and need for policies to be based on research evidence.
16 March 2018
FIEBRE aims to design new evidence-based guidelines to manage fever, thereby ensuring that patients get drugs that give them the best chance of recovery, and thereby help stop the spread of antimicrobial resistance (AMR), a major global health problem.
13 March 2018
ERGO is launching ALERRT, a multi-disciplinary consortium building a patient-centered clinical research network to respond to epidemics across sub-Saharan Africa. ALERRT aims to reduce the public health and socio-economic impact of disease outbreaks in sub-Saharan Africa by building a sustainable clinical and laboratory research preparedness and response network.
9 March 2018
In collaboration with Cambodian authorities, MORU are running the Village Drama Against Malaria project for the third year. The project, which runs in 10 remote villages in March 2018, aims to create awareness about malaria prevention and early treatment.
9 March 2018
Research led by Dr Marco Haenssgen has revealed how the complex cultural and social environment in developing countries can complicate the use of new diagnostic technologies to fight the global superbug crisis.
6 March 2018
Science Blog. Professor Guy Thwaites, Director of the Oxford University Clinical Research Unit, Vietnam, explains the discovery of yet another use for one of the most ubiquitous and ancient of drugs – aspirin.
23 February 2018
Melioidosis is a bacterial infection that quietly causes thousands of deaths each year. Meet Direk Limmathurotsakul, the doctor who made it his mission to make the world take notice.
20 February 2018
Myanmar-Oxford Clinical Research Unit (MOCRU) and partner Medical Action Myanmar (MAM) are performing a scrub typhus survey among fever patients attending the Puta-O clinic, a small, picturesque, secluded town surrounded by snow-capped Himalayan foothills in the far north of Myanmar over 1,500 km from Yangon.
9 February 2018
Over two-thirds of meat samples from Ho Chi Minh City were found to contain Salmonella bacteria, according to a study by the Oxford University Clinical Research Unit (OUCRU). Researchers purchased 117 samples of chicken meat, beef and pork from retail sites in 2016-2017; 68.4% of those samples were found to contain Salmonella bacteria.
9 February 2018
Applications are now being accepted for the AfOx Visiting Fellows Programme. This 4-6 weeks fellowship aims to facilitate collaborations, as well as foster research and teaching excellence in African institutions an the University of Oxford. Applicants must be residents of an African country and hold an appointment in an academic or research institution in an African country. Deadline 11th March 2018.
6 February 2018
Who will step up during the next decade to implement and integrate life-saving interventions and services for newborns? Decision-making leading to the implementation of newborn health services and interventions within broader health programmes requires multiple actors and levels of involvement. We invite you to contribute to the next phase of the discussion.