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New study evaluates accuracy of rapid diagnostic tests for malaria

A new study, published in Malaria Journal, assessed the accuracy of rapid malaria tests (RDTs) across 12 sites in India and found that these tests were sub-optimal for detecting P. vivax malaria.

Faulty malaria rapid test raises global concerns, say MORU researchers

A new study published in Malaria Journal warns that a widely used malaria rapid diagnostic test by Abbott Diagnostics may be delivering false-negative results, risking delayed treatment and fuelling malaria transmission. Researchers from SMRU have called for the test’s withdrawal, citing evidence from Southeast Asia.

Bridging the community voices: OUCRU Indonesia held the Kick-Off Meeting Community Forum for Health Research (ForuM)

In September, OUCRU Indonesia held the kick-off meeting of the Community Forum for Health Research (ForuM) — an initiative that connect OUCRU Indonesia researchers with lay public to strengthen OUCRU research and community engagement. The ForuM serves as OUCRU Indonesia’s Community Advisory Group (CAG) — a mechanism for two-way communication between researchers and the public. Members shared advice, guidance and feedback on study design, recruitment strategies, informed consent materials, cultural appropriateness, ethical considerations, and the communication of research findings.

MODRA Cohort 2: From ideas to action

Following the success of the first MODRA workshop in September, where participants developed strong research grant proposals, the MODRA Cohort 2 researchers reconvened at OUCRU Ho Chi Minh City for Workshop 2, focused on taking their projects from paper to practice.

Oxford strengthens strategic partnerships with Vietnam in health, education and climate innovation

The University of Oxford has signed three landmark agreements with leading Vietnamese partners, deepening collaboration across healthcare, higher education and sustainable aviation. The Tam Anh Research Institute has signed a Memorandum of Understanding with the International Health and Tropical Medicine Group from NDM Centre for Global Health Research, establishing the Tam Anh Oxford Partnership (TOP).

Ensitrelvir shows strong antiviral activity against COVID-19 in first head-to-head comparison with Paxlovid

The oral antiviral ensitrelvir is a highly effective treatment for COVID-19, showing potent in-vivo antiviral activity comparable to ritonavir-boosted nirmatrelvir (Paxlovid), say MORU, Mahidol and University of Oxford researchers in a major international study published in The Lancet Infectious Diseases.

OUCRU supports new WHO report tracking global antimicrobial resistance

The World Health Organization (WHO) has released its 2025 Global Antimicrobial Resistance and Use Surveillance (GLASS) Report, offering the most comprehensive global data on antimicrobial resistance (AMR) to date. Among the contributors were OUCRU Indonesia’s Professor Raph Hamers and Dr Gilbert Lazarus, whose systematic reviews provided critical insights into resistance trends. Their findings highlight rising resistance, especially in low-resource settings, and underscore the need for stronger surveillance and evidence-informed policy to address this growing health threat.

Innovative Oxford child anxiety treatment to be rolled out internationally

An effective online treatment for childhood anxiety developed by a team at the University of Oxford is to be adapted and tested in five countries in Asia and South America, with the aim of driving widespread implementation in the future.

At the Frontline of Infectious Diseases: My Experience as a Clinical Intern from Germany at OUCRU

German medical student Du Hanh spent a month at the Oxford University Clinical Research Unit (OUCRU) in Ho Chi Minh City, gaining firsthand experience in tropical and infectious diseases. From ICU rounds to research discussions, he discovered how OUCRU connects clinical care, research, and public health to make a real-world impact.

OUCRU Nepal and A*STAR IDL Sign MoU

OUCRU Nepal has officially signed a Memorandum of Understanding with the A*STAR Infectious Diseases Labs (A*STAR IDL), Singapore, to establish a collaborative partnership aimed at advancing research in infectious diseases. This strategic collaboration focuses on mutual interest with a shared focus on antimicrobial resistance, respiratory diseases, and vector-borne diseases, including associated neuroviral outcomes.

Sabina Dongol Selected for ISARIC Leadership Programme for Scientists

OUCRU-Nepal is proud to announce that Dr Sabina Dongol has been selected to join the first cohort of the ISARIC Leadership Programme for Scientists a global initiative aimed at empowering mid-career female researchers from Low- and Middle-Income Countries (LMICs) to become independent research leaders.

Antimalarial resistance deserves higher priority in global AMR strategy

In a new commentary for BMJ Global Health, University of Oxford researchers argue that antimicrobial resistance (AMR) interventions often ignore morally relevant differences between microbes. They highlight that antimalarial resistance disproportionately affects low- and middle-income countries, particularly children in sub-Saharan Africa, and deserves greater attention in global health research and intervention priorities. The team calls for more equitable resource allocation, policy change, and advocacy to ensure AMR responses are just and inclusive.

Anne Makena, Africa Oxford Initiative Co-Director steps down

Dr Anne Makena, has announced her decision to transition from the role of Co-Director of the Africa Oxford initiative. A founding member of the Africa Oxford Initiative, Dr Makena has overseen the establishment and rapid growth of AfOx from conceptualisation to scaling for almost a decade.

Seven CTMGH researchers awarded full professorships

We are delighted to announce that seven CTMGH researchers have been awarded the title of Professor, in recognition of their research achievements, contribution to teaching, and contribution to the general work of the Nuffield Department of Medicine.

Oxford named best university in the world for a record tenth consecutive year

Oxford University has been world number one in the Times Higher Education World University Rankings since 2017 - the longest time any university has held the position in the 21 annual editions of the rankings.

OUCRU contributes to defining the first core outcome measurement set for Dengue

A major international collaboration between ISARIC researchers at King’s College London and the Oxford University Clinical Research Trials Unit (OUCRU) has created the first global Core Outcome Measurement Set (COMS) for dengue clinical trials.

How research is shaping Kenya’s mental health future

Mental and substance use disorders are a major health concern in Kenya, yet remain underfunded and highly stigmatised. Despite policies like the Kenya Mental Health Policy, over 75% of those affected never receive professional care. Research institutions, including KEMRI–Wellcome Research Programme, have played a key role in shaping national and county-level responses. Progress is being made through community-based care, traditional healer collaboration, and the professionalisation of Community Health Promoters, but significant resource and workforce challenges remain.

FD-TACT malaria treatment trial launches patient recruitment in Rwanda

A Phase 3 pivotal trial, led by MORU and funded by Japan’s Global Health Innovative Technology Fund (GHIT), has begun to evaluate a novel fixed-dose triple artemisinin-based combination treatment (FD-TACT) for uncomplicated Plasmodium falciparum malaria.

Professor Edwine Barasa Appointed as Executive Director of the KEMRI-Wellcome Research Programme

Professor Edwine Barasa has been appointed as the Executive Director of the KEMRI-Wellcome Research Programme (KWRP), following the completion of a highly competitive recruitment process conducted by the Programme’s partners: the University of Oxford, KEMRI and Wellcome.

OUCRU workshop drives dialogue on early warning systems for climate-sensitive infectious diseases

Researchers, policymakers, and health professionals gathered at the Oxford University Clinical Research Unit (OUCRU) for a workshop on “Enablers and Barriers to Development and Implementation of Early Warning and Response Systems for Climate-Sensitive Infectious Diseases in Viet Nam.”

From Evidence to Impact: Transforming Sickle Cell Care in Kenya

Sickle cell anaemia is a genetic condition causing red blood cells to become sickle-shaped, leading to painful complications and other health issues. In Kenya, it is common in malaria-prone regions, where the sickle cell trait offers some protection. Ongoing research and a long-standing clinic in Kilifi have improved survival rates, with more adults living full lives. Collaboration with local health authorities and the Ministry of Health supports early diagnosis, care guidelines, and expanded regional services.

Kevin Marsh awarded RSTMH’s 2025 Sir Patrick Manson Medal

The Royal Society of Tropical Medicine and Hygiene's most prestigious award, the Sir Patrick Manson Medal, is being given this year to Professor Kevin Marsh, a Malariologist and Global Health Researcher. Professor Marsh is the Director of the Africa Oxford Initiative and Senior Adviser Science for Africa Foundation at the University of Oxford. His major research interests focus on immunity to and pathogenesis of malaria, and he has a particular interest in supporting science and scientific leadership across Africa.

New partnership aims to tackle antibiotic overuse in African children’s hospitals

PediSEP-1, a new study funded by the EDCTP3 Horizon programme, has launched to combat antimicrobial resistance (AMR) in African hospitals. The initiative introduces a risk-differentiated care approach identifying low-risk children who can be safely discharged early with minimal or no antibiotics supported by targeted parental education and ‘virtual ward’ follow up by phone. The project seeks to reduce antibiotic overuse and AMR transmission, and increase system efficiency

Building Vietnam’s Clinical Trial Future: OUCRU and Partners at the Forefront

On 26 September 2025, leading researchers, policymakers, and international partners gathered in Hanoi for the Workshop on Clinical Trial Opportunities in Viet Nam, co-organised by the World Health Organization, Hanoi Medical University, and the Oxford University Clinical Research Unit (OUCRU). The event marked an important step in strengthening Vietnam’s clinical trial ecosystem, aligning national ambitions with global health innovation.

MORU Community Advisory Boards meet in Bangkok

From 21-22 Aug, twenty five MORU Major International Programme (MIP) colleagues attended the second CAB-NET meeting in Bangkok and online. Run by MORU Bioethics & Engagement (B&E), CAB-NET is a network that bring together the facilitators of community advisory boards (CABs) run by the MORU MIP to share activity updates, ideas and best practices, training, and network.

Joel Tarning awarded RSTMH’s 2025 Chalmers Medal

Professor Joel Tarning, head of MORU’s Clinical Pharmacology Department, has been honoured with the award of the Royal Society of Tropical Medicine and Hygiene’s Chalmers Medal for his exceptional contribution to the field of clinical pharmacology of neglected tropical diseases, and in particular antimalarial therapy.

A migrant mother’s 4-hr walk for antenatal care

On the Thai-Myanmar border, life is often a daily struggle, especially for expectant mothers like migrant day labourer Daw Mu (name changed for privacy), who lives in a village near Jaydi Koh in Tak Province’s Phop Phra District. Now three months pregnant with her second child, Daw Mu must walk 4 hours to the Jaydi Koh SMRU/BHF outreach clinic for antenatal care, often with her four-year-old son by her side.

MODRA Cohort 2 begins: Empowering the next generation of leaders in global health

Fifteen emerging scientists from South and Southeast Asia begin an 18-month journey with MODRA. Together, they are gaining the skills to lead research that makes a difference in global health.

New study find treatment for Chagas disease is excessive

A new study has found the current recommended treatment for Chagas disease could be given over a substantially shorter time period and still be as effective.

Bridging science and practice to improve the outcome of patients with dengue

Dengue cases in Ho Chi Minh City surged by 170% in 2025, straining hospitals and affecting both children and adults. In response, OUCRU and partners held a workshop with over 200 health professionals to share research, identify clinical gaps, and advance collaborative efforts for improved dengue diagnosis and treatment.

OUCRU researchers have a leading role in developing first International Clinical Practice Guideline for Tuberculous Meningitis

OUCRU researchers have played a leading role in developing the world’s first international clinical practice guideline for tuberculous meningitis (TBM), now published in The Lancet Infectious Diseases.

New study maps immune cells fuelling harmful inflammation in tuberculous meningitis

Tuberculous meningitis (TMB) harms not only through infection, but also through the body’s own overactive immune response. Using single-cell RNA sequencing, OUCRU scientists have identified specific immune cells in the brain that may be driving this harmful inflammation. Their study established a cutting-edge cellular method to identify new therapeutic targets for host-directed therapy, aimed at improving survival and reducing immune-mediated brain injury in TBM patients.

OUCRU release report on intensive care training programme in Vietnam

After more than three years of collaboration, OUCRU and Dragon Capital are pleased to announce the release of the final report of the Intensive Care Training Programme for Life-Threatening Infectious Diseases in Vietnam.

Tracking resistance: Mapping the spread of drug-resistant malaria

On World Mosquito Day, Dr Lucy Harrison, postdoctoral researcher at Oxford’s Infectious Diseases Data Observatory (IDDO) at the Centre for Tropical Medicine and Global Health, reflects on the global impact of the mosquito and her research into malaria drug resistance.

SMRU honored at One Health Conference

On 13 August 2025, SMRU received the “One Health Champion” First Prize for its response to a cholera outbreak along the Thai–Myanmar border. Awarded at a national One Health conference, the recognition highlights SMRU’s excellence in cross-border disease surveillance and public health response through collaborative, sustainable policy efforts.

OUCRU and partners launch Kleb-CASAVA project

OUCRU and partners have officially launched the Klebsiella pneumoniae Community Acquired Infections Surveillance And Vaccine Development (Kleb-CASAVA) project. This collaborative initiative will strengthen surveillance of community-acquired Klebsiella pneumoniae infections and advance vaccine development to address the growing global threat of antimicrobial resistance

First volunteers receive Rift Valley fever vaccine in Kenya Phase II trial

On 8 July 2025, researchers at the KEMRI-Wellcome Trust Research Programme began the Phase II trial of the ChAdOx1 RVF vaccine in Kilifi, Kenya—the most advanced Rift Valley fever vaccine study in an outbreak-prone region. Led by Oxford University and funded by CEPI, this milestone brings us closer to a licensed vaccine for protecting lives and livelihoods.

Severe nurse shortages in Kenya undermine newborn care, despite advancements

A multi-disciplinary study by KEMRI-Wellcome Trust, Harnessing Innovation in Global Health for Quality Care (HIGH-Q), has revealed how workforce issues influence the quality of care in newborn units. The research highlighted the effect of severe nurse staffing shortages in Kenyan hospitals as a major obstacle to providing quality care for newborns.

Indonesia to host first dual-species malaria vaccination trial

OUCRU Indonesia is preparing a Phase 2 clinical trial of a malaria vaccination designed to protect against the two most widespread malaria parasites, Plasmodium falciparum and Plasmodium vivax. The trial, to be conducted in Keerom, Papua, will be the first to test a dual-species malaria vaccination in humans.

Simple new method that measures viral clearance means antibody treatments for COVID and ‘flu can be quickly assessed for effectiveness, say MORU researchers

Measuring the rate of viral clearance from the back of the mouth in patients with mild infections can be used to determine quickly and inexpensively if an antibody is effective in future COVID-19, influenza and other respiratory virus pandemics, say researchers in a letter published today in The Lancet.

Global Action Needed to Tackle Noma Disease

Greater surveillance and well-designed epidemiological studies for noma should be a research priority. A new BMJ Global Health paper reveals major gaps in research on noma, a severe and often fatal oral disease affecting children in low-resource settings. Despite WHO recognition of noma as a neglected tropical disease, limited data exists on its causes, burden, and treatment. The study calls for standardised reporting, increased surveillance, and improved early detection. Conducted by IDDO and WHO, the review analysed 366 studies to provide a comprehensive foundation for future research and policy action.

What I learned as a UK clinical intern at OUCRU Vietnam: infectious diseases and the realities of vaccine inequality

Nandita Shenolikar, a final-year UK medical student, completed a clinical internship in infectious diseases at OUCRU in Ho Chi Minh City. She tells us how her placement offered unique exposure to severe infections, highlighting global vaccine disparities and deepening her medical knowledge. Nandita's experience also fostered friendships, cultural exploration and a lasting connection to Vietnam.

Policy in action: A Princeton student’s internship at OUCRU Vietnam

Alayshja Bable, a Princeton University student, interned with OUCRU Vietnam’s Policy Engagement team, conducting interviews to evaluate how research informs health policy. Her work strengthened OUCRU’s strategy while deepening her understanding of Vietnam’s policy landscape. The experience also enriched her personal growth and affirmed her commitment to human rights work.

OUCRU and HSPI sign MoU to advance health research collaboration

OUCRU and the Health Strategy and Policy Institute have signed a Memorandum of Understanding to promote joint research and evidence-based health policy. The agreement marks a significant step toward a long-term interdisciplinary collaboration.

New research finds that ivermectin could help control malaria transmission

A collaborative new study involving KEMRI-Wellcome Trust researchers has highlighted a new way to control malaria transmission. The study found that ivermectin, a drug normally used for neglected tropical diseases, led to a 26% reduction in new malaria infections among children aged 5-15.

From Despair to Collective Action: Reflections from the Global Health Solidarity Open Forum 2025

The Global Health Solidarity Open Forum 2025 convened over 150 global participants to explore solidarity in research and practice. Speakers emphasised power redistribution, equitable partnerships, and community-led engagement in global health. Discussions highlighted the importance of shifting from aid to collaboration, ensuring solidarity becomes a driving force in shaping just, resilient health systems.

Community discussion: What do underserved populations at risk of Hepatitis C Virus need the most?

As part of efforts to improve Hepatitis C care for underserved groups, OUCRU hosted a dialogue bringing together community members, social scientists and insurance representatives. Participants, including people who inject drugs, LGBT+ individuals and low-income groups, discussed barriers to accessing health insurance despite policy improvements. Challenges include complex hospital systems, documentation issues, limited awareness, financial constraints and privacy concerns. The session highlighted the importance of continued community-based participatory research to address health inequities and strengthen support networks.

Two nights of talks for Pint of Science Laos 2025

In May 2025, LOMWRU organised the 4th Pint of Science event in Vientiane, Laos, as part of the global Pint of Science festival. The successful event, open to the general public, had local researchers from public health, wildlife conservation, and geology giving fun and interesting talks over two nights, giving insights into how their work impacts Laos.

15 emerging Asian global health researchers selected to join MODRA

The MORU – OUCRU Discovery Research Academy (MODRA) announces its 2025 cohort of emerging researchers in global health and infectious diseases.

Who held the microphone during the health crisis? A case study from Indonesia

How participatory mapping helped identify trusted voices in health crisis communication during Indonesia’s COVID-19 response? This article highlights the role of public trust, local leadership, and culturally relevant messaging in shaping more inclusive and effective communication strategies for future outbreaks.

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