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This article reviews emerging Raman techniques (Spatially Offset and Transmission Raman Spectroscopy) for non-invasive, sub-surface probing in process control and forensic applications. New capabilities offered by these methods are discussed and several application examples are given including the non-invasive detection of counterfeit drugs through blister packs and opaque plastic bottles and the rapid quantitative analysis of the bulk content of pharmaceutical tablets and capsules without sub-sampling.

More information Original publication

DOI

10.1007/s11095-008-9587-2

Type

Journal article

Publication Date

2008-10-01T00:00:00+00:00

Volume

25

Pages

2205 - 2215

Total pages

10

Addresses

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Keywords

Capsules, Tablets, Spectrum Analysis, Raman, Technology, Pharmaceutical, Drug Contamination, Fraud, Forensic Sciences, Quality Control, Signal Processing, Computer-Assisted