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Disease caused by Cryptococcus gattii typically manifests as meningoencephalitis or pulmonary nodules. Endobronchial lesions are rare, and most cases are caused by Cryptococcus neoformans. We describe here a case of endobronchial disease in a child caused by C gattii. The disease spectrum in this patient was notable for the discovery of anti-granulocyte macrophage colony-stimulating factor autoantibodies.

Original publication

DOI

10.1093/jpids/piy100

Type

Journal

Journal of the Pediatric Infectious Diseases Society

Publication Date

02/2020

Volume

9

Pages

67 - 70

Addresses

Department of Infectious Diseases and Microbiology, Children's Hospital Westmead, New South Wales, Australia.

Keywords

Bronchi, Brain, Animals, Phascolarctidae, Humans, Meningitis, Cryptococcal, Cryptococcosis, Bronchial Diseases, Airway Obstruction, Meningoencephalitis, Granulocyte-Macrophage Colony-Stimulating Factor, Autoantibodies, Antifungal Agents, Magnetic Resonance Imaging, Bronchoscopy, Enzyme-Linked Immunosorbent Assay, Child, Female, Cryptococcus gattii