Time to reconsider the role of ribavirin in Lassa fever

Salam AP., Cheng V., Edwards T., Olliaro P., Sterne J., Horby P.

Ribavirin is the only available Lassa fever treatment. The rationale for using ribavirin is based on one clinical study conducted in the early 1980s. However, reanalysis of previous unpublished data reveals that ribavirin may actually be harmful in some Lassa fever patients. An urgent reevaluation of ribavirin is therefore needed.

DOI

10.1371/journal.pntd.0009522

Type

Journal

PLOS Neglected Tropical Diseases

Publisher

Public Library of Science (PLoS)

Publication Date

08/07/2021

Volume

15

Pages

e0009522 - e0009522

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