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An increase of acute hepatitis of unknown aetiology has been reported among children in multiple countries worldwide. With a rapid online survey among hospitals in and outside of Europe, we describe case numbers recorded from 1 January to 18 April 2022 vs the previous 5 years. Of 24 countries that responded, we identified 5/17 European and 1/7 non-European countries with an elevation in probable cases of unexplained acute hepatitis, and severe cases were elevated in five European countries.

Original publication





Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

Publication Date





Department of Viroscience, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.


Acute hepatitis study group, Humans, Hepatitis, Acute Disease, Child, Europe, Surveys and Questionnaires