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Transmission Raman spectroscopy is employed for the first time to analyse model formulations comprising tabletted cocrystals. The ability of transmission Raman to differentiate between formulations on the basis of both drug loading and drug chemistry (cocrystal versus separate components) is investigated.

Original publication

DOI

10.1039/c2an35216h

Type

Journal

The Analyst

Publication Date

07/2012

Volume

137

Pages

3052 - 3057

Addresses

School of Pharmacy, University of Nottingham, Nottingham, NG7 2RD, UK. jonathan.burley@nottingham.ac.uk

Keywords

Tablets, Spectrum Analysis, Raman, Principal Component Analysis, Automation, Quality Control