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Admission procalcitonin measurements and microbiology results were available for 1040 hospitalized adults with coronavirus disease 2019 (from 48 902 included in the International Severe Acute Respiratory and Emerging Infections Consortium World Health Organization Clinical Characterisation Protocol UK study). Although procalcitonin was higher in bacterial coinfection, this was neither clinically significant (median [IQR], 0.33 [0.11–1.70] ng/mL vs 0.24 [0.10–0.90] ng/mL) nor diagnostically useful (area under the receiver operating characteristic curve, 0.56 [95% confidence interval, .51–.60]).

Original publication

DOI

10.1093/ofid/ofac179

Type

Journal

Open Forum Infectious Diseases

Publisher

Oxford University Press

Publication Date

01/05/2022

Volume

9

Keywords

coinfection, COVID-19, FFR, procalcitonin, SARS-CoV-2