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Baricitinib – an anti-inflammatory treatment for rheumatoid arthritis– is being investigated in the RECOVERY trial, the world’s largest clinical trial of treatments for patients hospitalised with COVID-19, taking place in 177 hospital sites across the UK and with over 33,000 patients recruited so far. As an anti-inflammatory, baricitinib may block the signalling activity of cytokine molecules which contribute to the hyper-inflammatory state seen in severe COVID-19. It is thought that baricitinib may act also have some anti-viral activity. The other treatments currently being investigated in the RECOVERY trial are Regeneron’s antibody cocktail, Aspirin and Colchicine.

Chemical composition of the molecule Baricitinib, C16H17N7O2S

Audrey Dubot-Peres

Audrey Dubot-Peres - Head of Virology

Christiane Dolecek

MD PHD FRCP Christiane Dolecek - Professor of Global Health

Louise Thwaites

BSc MBBS MRCP MD DMSMed MLCOM Louise Thwaites - Professor of Experimental Critical Care

Phaik Yeong Cheah

Phaik Yeong Cheah - Professor of Global Health

Evelyne Kestelyn

Evelyne Kestelyn - Head of the Clinical Trials Unit

Bridget Wills

Bridget Wills - Professor of Tropical Medicine

Quyen Tran

Quyen Tran - TAMRI-Oxford Programme Strategic Lead.

Beatrice Amboko

Beatrice Amboko - Teaching and Research Associate

Ken Ong

Ken Ong - Teaching and Research Associate

Julie Huynh

Julie Huynh - Clinical Research Paediatrician

Paul Newton

Paul Newton - Professor of Tropical Medicine

Ghulam Rhahim Awab

Ghulam Rhahim Awab - Senior researcher

Wirichada Pan-ngum

Wirichada Pan-ngum - Associate Professor

Direk Limmathurotsakul

Direk Limmathurotsakul - Professor of Infectious Disease Epidemiology

Richard Hoglund

Richard Hoglund - Head of Pharmacometrics

Mehul Dhorda

Mehul Dhorda - DeTACT-Africa Coordinator / Head of Specimen Management Laboratory

Abhilasha Karkey

Abhilasha Karkey - Associate Professor

Buddha Basnyat

Buddha Basnyat - Associate Professor

Raph Hamers

MD PhD Raph Hamers - Associate Professor in Infectious Diseases

Stuart Blacksell

BAppSc MPH PhD RBP(ABSA) FASM FFSc(RCPA) TechIOSH Stuart Blacksell - Professor of Tropical Microbiology

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