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Dr Buddha Basnyat

Dr Buddha Basnyat

Podcast interview

High altitude illness can be prevented by a simple rule: don't go too high, too fast. Drugs can also be used, and Dr Basnyat showed that a much lower dose of Diamox, a commonly used drug, is as effective. His research also focusses on the effect of high altitude on pilgrims, an older, poorer and more vulnerable population.

Buddha Basnyat

Director of Oxford University Clinical Research Unit-Nepal

OUCRU Nepal

Oxford University Clinical Research Unit-Nepal (OUCRU-NP) is hosted by Patan Hospital and the Patan Academy of Health Sciences in Kathmandu Nepal and works in close collaboration with the Nepal Health Research Council at the Nepalese Ministry of Health and Population. Our mission within the Patan Hospital, the Patan Academy of Health Sciences and OUCRU-NP is to build a strong critical mass of young Nepalese clinician scientists who can help build Nepal's scientific and clinical future.

OUCRU-NP was initiated in the summer of 2003 following a visit to Nepal by Professor Jeremy Farrar (who headed OUCRU-Vietnam at that time) after an exchange of letters with Dr Buddha Basnyat (Consultant, Patan Hospital) in the New England Journal of Medicine, subsequent to a review article by Professor Farrar and colleagues on enteric fever.

In this period of about 13 years, this Unit at Patan Hospital has published many ground-breaking randomized controlled trials (RCTs) on enteric fever in well-respected infectious disease journals like the Lancet Infectious Diseases. This Unit has also clearly documented other causes of undifferentiated febrile illness besides enteric fever. Recent research from our Unit showed that typhus commonly mimics typhoid and that, importantly, the treatment is different. The spin-offs of these RCTs have included the study of the epidemiology of enteric fever and crucially research in antimicrobial resistance, an understated problem in South Asia. Very recently we have also been involved in public engagement throughout the country with the Epidemiology and Disease Control Division of the Government of Nepal so that our research findings are not just confined to academia.

Dr Banyat's research interest lies in working with and helping young clinicians in the study of high altitude illness and undifferentiated febrile illness in the tropics, both common but neglected problems in Nepal.

Patan Hospital, Kathmandu
Helping a patient with enteric fever in her home

Key publications

Recent publications

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