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Baricitinib – an anti-inflammatory treatment for rheumatoid arthritis– is being investigated in the RECOVERY trial, the world’s largest clinical trial of treatments for patients hospitalised with COVID-19, taking place in 177 hospital sites across the UK and with over 33,000 patients recruited so far. As an anti-inflammatory, baricitinib may block the signalling activity of cytokine molecules which contribute to the hyper-inflammatory state seen in severe COVID-19. It is thought that baricitinib may act also have some anti-viral activity. The other treatments currently being investigated in the RECOVERY trial are Regeneron’s antibody cocktail, Aspirin and Colchicine.
Oxford academics awarded European Research Council Advanced Grants for cutting-edge research
17 June 2025
Professor Deirdre Hollingsworth and six researchers at the University of Oxford have been awarded Advanced Grants from the European Research Council, each worth up to €2.5 million over a period of five years.
Bring time back to care with AI-assisted applications for dengue in Vietnam
16 June 2025
OUCRU has developed D‑SCAPE, a wearable device, and D‑CAT, an AI-led clinical decision tool, to enhance dengue management in Vietnam. These innovations automate vital monitoring and analyse patient data to predict deterioration, allowing timely action. They alleviate frontline workloads and improve proactive care in resource-constrained hospitals.
Interview with Trudie Lang, mpox surging in Sierra Leone
13 June 2025
As mpox cases rise in Sierra Leone, Professor Trudie Lang helps us understand the implications of the continuing spread of the disease, why it matters and how global efforts to tackle the outbreak are progressing.
Research finds new metabolic clues to survival in tuberculous meningitis
12 June 2025
In a collaborative new study led by OUCRU, researchers have found that tryptophan in cerebrospinal fluid is a determinant of lower survival in people with tuberculous meningitis. These findings suggest the possibility that other metabolites could also predict patient outcomes.
WHO delegation visits OUCRU to strengthen collaboration on infectious disease research and surveillance
12 June 2025
A WHO delegation visited OUCRU and the Hospital for Tropical Diseases (HTD) to explore collaborative efforts in infectious disease research, diagnostics, and surveillance. The institutions showcased achievements in outbreak response and genomic sequencing. The visit strengthened ties with WHO, highlighting OUCRU and HTD’s regional leadership and commitment to advancing health security and training opportunities.
Nipah virus vaccine granted European Medicines Agency PRIME designation
11 June 2025
Co-led by researchers at the Pandemic Sciences Institute, the Nipah virus has been granted PRIME designation. This recognises the vaccine’s potential to address the unmet medical need arising from the devastating Nipah virus disease, which can be fatal in up to 85% of cases.
Circus arts shine spotlight on AMR in Cambodian communities
4 June 2025
In May 2025, circus performances were used to educate Cambodian youth on the correct use of antibiotics. Misuse of antibiotics is a major driver of bacterial antimicrobial resistance (AMR) worldwide. The wide availability of antibiotics over the counter in Cambodia and linguistic issues make it difficult for younger Cambodians to understand when antibiotic use is appropriate.
AI and big data in clinical care for infectious diseases in Vietnam
3 June 2025
Oxford University Clinical Research Unit (OUCRU) and the Hospital for Tropical Diseases in Ho Chi Minh City recently hosted a scientific conference titled “Applying Artificial Intelligence and Big Data in Clinical Practice for Infectious Diseases.”
Nurturing Tomorrow’s Research Leaders: A Celebration of Mentorship and Discovery
3 June 2025
The KEMRI-Wellcome Trust Schools Engagement Programme (SEP) celebrated the achievements of its School Leavers Attachment Scheme (SLAS) through a poster event. Twelve Kilifi students explored real-world research, mentored by experts. SEP’s immersive, hands-on experience builds scientific skills, confidence, and curiosity, inspiring the next generation of researchers and future science leaders.
OUCRU and partners chart a “Roadmap to the Future of Clinical Trials in Vietnam”
2 June 2025
A new report charts a roadmap to make Vietnam a top-three ASEAN destination for clinical trials by 2030. It outlines challenges and solutions to unlock economic and health benefits. Aligning with global best practice can position Vietnam as a hub for life-saving research and innovation.
Ambitious project to develop low-cost genome sequencing for pathogens
28 May 2025
A low-cost genome sequencing technique that was used by thousands of laboratories globally to spot COVID-19 variants will be extended to cover all pathogens, in an ambitious new Wellcome Trust-funded project launched today. The ARTIC-2 project is led by the University of Birmingham and brings together researchers from the Democratic Republic of Congo, Ghana and Kenya with expertise in responding to numerous viral threats using genomic surveillance, including recent outbreaks of Ebola virus and Mpox in Africa.
Landmark DeTACT project holds final Investigators’ meeting
26 May 2025
On 6-7 May in Zanzibar, Tanzania, the final investigators’ meeting of the Development of Triple Artemisinin-based Combination Therapies (DeTACT) project brought together 35 investigators from participating institutions in Bangladesh, Cambodia, Guinea, Nigeria, Niger, Tanzania, The Gambia, Rwanda, Singapore, and MORU, along with key partners from Fosun Pharma, Medicines for Malaria Venture (MMV), the WHO Global Malaria Programme, and the UK Foreign, Commonwealth and Development Office (FCDO), which funded the project over the past seven years.
UPDATE Myanmar earthquake: MAM and MOCRU provide life-saving response
23 May 2025
On 28 March 2025, a powerful earthquake (magnitude 7.8) devastated central Myanmar, with the epicentre near Mandalay, the country’s second largest city, and home to 1.5 million people. On 1 April, Medical Action Myanmar (MAM) and the Myanmar Oxford Clinical Research Unit (MOCRU) sent 70 staff to launch an emergency response.
CTMGH LinkedIn takeover by MSc IHTM students starts 3 June
23 May 2025
Get ready! - the CTMGH LinkedIn takeover begins on Tuesday 3 June and eight students from our MSc in International Health and Tropical Medicine, who are currently working around the world, will be sharing their research placement experience.
Rethinking Autism: Bridging gaps in care, culture and understanding
20 May 2025
Autism Spectrum Disorder is a lifelong condition affecting communication, behaviour, and sensory experiences. In Kenya, stigma, misinformation, and limited access to care hinder early diagnosis and support. Cultural beliefs and lack of specialist services further challenge families. KWTRP NeuroDev Project is improving understanding through genetic research, while new interventions like caregiver training are being trialled. Experts call for greater awareness, early screening, and inclusive policies to support autistic individuals and their families.
The power to take care of your mental health is within the community
20 May 2025
This May, countries worldwide mark Mental Health Awareness Week under the theme community. OUCRU highlights research from Vietnam showing how social connections support mental wellbeing. With localised resources and expert guidance, we aim to reduce stigma, encourage open conversations, and empower individuals and communities to care for mental health—together.
Researchers awarded Associate Professorships
20 May 2025
We are delighted to announce that Abdirahman Abdi and Alice Norton have been awarded the Associate Professor title, in recognition of their research achievements, contribution to teaching, and contribution to the general work of the Nuffield Department of Medicine.
Engaging stakeholders to build a Kenyan learning health system success in Vice-Chancellor’s Awards
20 May 2025
Work led by a NDM Centre for Global Health Research (CGHR) and KEMRI-Wellcome team `Engaging stakeholders to build a Kenyan learning health system’ was recognised as winner of the Vice-Chancellor’s Research Engagement Award on Thursday 15 May where the team was represented by Professor Mike English.
Oxford and Thai Health Officials Sign Agreement on Infectious Disease Control
15 May 2025
On 13 May 2025, representatives from the University of Oxford and the Tak Provincial Public Health Office signed a Memorandum of Understanding to strengthen collaboration on infectious disease prevention and control along the Thai–Myanmar border. The agreement focuses on joint research into key diseases affecting the border population.
IHTM shortlisted for Vice-Chancellor’s Awards 2025
14 May 2025
The MSc in International Health and Tropical Medicine (IHTM) at the University of Oxford has been shortlisted for two 2025 Vice-Chancellor’s Awards, recognising the programme’s outstanding contributions to education and student support across the University.