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A global study to test if either chloroquine or hydroxychloroquine can prevent COVID-19 in vital frontline healthcare workers will open to UK participants at hospital sites in Brighton and Oxford today.

Close up on the hands of a health care worker taking a blood sample

Oxford-led researchers develop a low-cost rapid test to identify heat-damaged vaccines

Researchers from Medicine Quality Research Group, the University of Oxford and their collaborators have developed and evaluated a novel low-cost, rapid method to identify heat-exposed sucrose-containing vaccines without the need for sophisticated laboratory equipment.

Research Spotlight: The IRONMUM Trial at SMRU

IRONMUM is one example of SMRU’s long-standing collaboration with global partners to address critical health challenges in low- and middle-income settings. Through partnerships with institutions such as the University of Oxford and the Mahidol Oxford Tropical Medicine Research Unit (MORU), SMRU conducts research that is firmly grounded in local realities, ensuring that preventive strategies and treatments are effective where they are needed most. Working on the Thailand–Myanmar border since 1986, SMRU combines research, clinical care, and humanitarian action to improve the health of mothers, children, and vulnerable populations affected by infectious diseases and limited access to healthcare.

International collaboration launches largest-ever therapeutics trial for patients hospitalised with dengue

A landmark international research collaboration has launched the largest clinical trial ever conducted to test therapeutics for moderate-severe dengue, a mosquito-borne viral disease that continues to spread rapidly driven by climate change and globalisation.

Global Consortium Launched to Develop Next-Generation Malaria Vaccine

A new international consortium, MVC-2G, has been launched to develop a next-generation malaria vaccine offering broader protection by targeting multiple stages of the parasite’s lifecycle. Co-led by KWTRP and supported by African, UK and EU partners, the five-year effort aims to improve vaccine efficacy. KWTRP is committed to producing rigorous clinical evidence to ensure new tools meet the needs of African communities most affected by malaria, supporting regional vaccine research, delivery, and long-term impact.

Blood test predicts risk of death in acutely ill children in lower-income countries

An international study has identified a blood-based indicator of intestinal damage and inflammation that strongly predicts mortality in sick children. The new biomarker could help to identify those children at greatest risk of dying after hospitalisation in parts of the world with limited resources.

OUCRU trials AI-powered wearables for early warning of severe dengue

AI applications in dengue monitoring and prediction are showing encouraging early signals, with new models achieving around 80% accuracy in forecasting severe progression up to two hours in advance. The Oxford University Clinical Research Unit (OUCRU) presented these findings at the Dengue Summit 2025, organised by Ho Chi Minh City Pasteur Institute.

Avoidable pitfalls on the path to health financing self-reliance in low-income and middle-income countries

Low- and middle-income countries (LMICs) are facing an urgent and complex challenge: how to transition to greater self-sustainability in health financing amid declining donor support. While this shift is inevitable, the policy responses it elicits carry significant implications for health system equity and access.

Rapid, low-cost tests can help prevent child deaths from contaminated medicinal syrups

Researchers at the University of Oxford and their collaborators have demonstrated that simple, rapid, and inexpensive tests can detect deadly contaminants in medicinal syrups - contaminants that have tragically led to the deaths of hundreds of children worldwide.

Community Engagement in Antimicrobial Stewardship Programmes Implementation – 60HN ASPARNet

The study titled “Evaluating Antimicrobial Stewardship strategies and capacity building through Participatory Action Research and a Network approach in Vietnam” (60HN – ASPARNet) continues to implement activities to promote Antimicrobial Stewardship (AMS) programmes across hospitals participating in the network.

Data platform will play a vital role in future VL research

A new publication authored by IDDO’s Visceral Leishmaniasis (VL) Scientific Advisory Committee sets out a research agenda for VL, and describes how IDDO established and developed a data platform that enables data reuse for crucial historical data.

‘Creeping catastrophe’: Climate change is driving global rise in infectious diseases, leading health experts warn

Infectious diseases such as malaria, dengue, and tuberculosis are considered to pose as great a challenge to global health as new or emerging pathogens, according to a major international study led by The Global Health Network at Oxford’s Nuffield Department of Medicine and commissioned by Wellcome.

Youth Peer Educator Combat AMR: Indonesian Youth Action in Antimicrobial Resistance’s Stewardship

Knowledge and beliefs about antibiotics continue to shape emerging health behaviours in Indonesia. With support from OUCRU, PAPRA empowered young people to create learning resources to promote responsible antibiotic use among their peers.

Shaping Oxford’s Vision for Global Health in a Period of Turbulence

The first Oxford Global Health Summit united colleagues across the University to drive a bold, collaborative vision for global health.

Oxford Global Health welcomes Ghana’s High Commissioner for engagement on malaria and strengthening collaboration

Oxford Global Health welcomed Ghana’s High Commissioner and her delegation for a day of discussions on malaria elimination and future collaboration.

Optimizing Newborn Care: Inside the NeoSep1 trial

Neonatal sepsis, worsened by antimicrobial resistance (AMR), remains a major cause of infant deaths in Africa. The NeoSep1 Trial, led by GARDP and KEMRI, is testing tailored antibiotic combinations for newborns. This research aims to update WHO guidelines, strengthen local research capacity, and improve access to effective treatments across low-resource settings.

Analysis of SMRU samples could lead to vaccine for multiple childhood infections

The first large-scale genomic exploration of H. influenzae, a bacteria that causes 200m infections per year in children worldwide, has revealed extensive antibiotic resistance and uncovered genetic clues that could help in future vaccine development, say researchers from Wellcome Sanger Institute, the Universities of Oxford and Oslo, and MORU’s Shoklo Malaria Research Unit (SMRU) and Cambodia-Oxford Medical Research Unit (COMRU).

Rose McGready honoured for her work to improve healthcare for Thai-Myanmar border communities

On 17 Nov at a ceremony in Canberra, Prof Rose McGready, Deputy Director of the Shoklo Malaria Research Unit (SMRU), was honoured with the 2026 ACT Australian of the Year Award for her extraordinary dedication over 30 years to improving healthcare for displaced and marginalised communities along the Thai-Myanmar border which, coupled with clinical and research work that has changed the treatment of malaria around the world, particularly for pregnant and breastfeeding women, has saved the lives of countless mothers and their babies.

Communicate Antimicrobial resistance (AMR) using community-based, co-created media

World AMR Awareness Week (18–24 November) promotes global action against antimicrobial resistance (AMR) under the theme “Act Now: Protect Our Present, Secure Our Future.” Vietnam, among the countries with the highest antibiotic resistance rates, faces widespread antibiotic misuse. OUCRU and partners have launched innovative, youth-focused engagement initiatives—including animated videos, theatre performances, and peer-led projects in Vietnam, Indonesia, and Nepal—to raise awareness, correct misconceptions, and connect science with everyday experiences.

KWTRP holds annual Media Advisory Group meeting

KWTRP held its annual Media Advisory Group (MAG) meeting on 6–7 November 2025, under the theme Reflect and Engage: Strengthening Media–Researcher Collaboration. Thirteen members joined the two-day event, which featured field visits, breakout discussions, and strategic planning sessions. MAG has grown into a platform for hands-on collaboration, combining journalism, community insight, and digital media expertise to enhance research communication and foster impactful, trusted public engagement in health research.

GRAM invites researchers to explore AMR data in repository

After gathering one of the largest collections of individual patient data on antimicrobial resistance (AMR) in the world, the Global Research on Antimicrobial Resistance (GRAM) Project is now inviting researchers to use this valuable resource in their own studies. The AMR data repository, hosted by the Infectious Diseases Data Observatory (IDDO), now covers nearly 70 countries and 250,000 patients, after launching last year to provide a secure, sustainable platform for global AMR data sharing. Holdings currently include 38 datasets from 24 different (GRAM) Project collaborators.

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