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IDDO has launched a new global Chagas scientific collaboration with the Drugs for Neglected Diseases initiative (DNDi). The new platform will collate and standardise data to accelerate better treatments for the 6–7 million people worldwide with Chagas disease.

Triatominae on a gloved finger © CDC James Gathany

Using effective media strategies to bridge gaps to hard-to-reach populations: case studies in Vietnam and Indonesia

OUCRU has developed culturally tailored strategies to improve vaccine communication and uptake in diverse communities across Vietnam and Indonesia. From training village health collaborators and co-creating storytelling films in Dak Lak to animated videos for malaria trial recruitment among Indonesian soldiers, these efforts highlight the power of locally relevant, creative engagement. By addressing structural barriers, cultural sensitivities and trust, OUCRU’s initiatives demonstrate how community-informed approaches can enhance public health research and support better health outcomes.

Bring time back to care with AI-assisted applications for dengue in Vietnam

OUCRU has developed D‑SCAPE, a wearable device, and D‑CAT, an AI-led clinical decision tool, to enhance dengue management in Vietnam. These innovations automate vital monitoring and analyse patient data to predict deterioration, allowing timely action. They alleviate frontline workloads and improve proactive care in resource-constrained hospitals.

Research finds new metabolic clues to survival in tuberculous meningitis

In a collaborative new study led by OUCRU, researchers have found that tryptophan in cerebrospinal fluid is a determinant of lower survival in people with tuberculous meningitis. These findings suggest the possibility that other metabolites could also predict patient outcomes.

WHO delegation visits OUCRU to strengthen collaboration on infectious disease research and surveillance

A WHO delegation visited OUCRU and the Hospital for Tropical Diseases (HTD) to explore collaborative efforts in infectious disease research, diagnostics, and surveillance. The institutions showcased achievements in outbreak response and genomic sequencing. The visit strengthened ties with WHO, highlighting OUCRU and HTD’s regional leadership and commitment to advancing health security and training opportunities.

AI and big data in clinical care for infectious diseases in Vietnam

Oxford University Clinical Research Unit (OUCRU) and the Hospital for Tropical Diseases in Ho Chi Minh City recently hosted a scientific conference titled “Applying Artificial Intelligence and Big Data in Clinical Practice for Infectious Diseases.”

OUCRU and partners chart a “Roadmap to the Future of Clinical Trials in Vietnam”

A new report charts a roadmap to make Vietnam a top-three ASEAN destination for clinical trials by 2030. It outlines challenges and solutions to unlock economic and health benefits. Aligning with global best practice can position Vietnam as a hub for life-saving research and innovation.

The power to take care of your mental health is within the community

This May, countries worldwide mark Mental Health Awareness Week under the theme community. OUCRU highlights research from Vietnam showing how social connections support mental wellbeing. With localised resources and expert guidance, we aim to reduce stigma, encourage open conversations, and empower individuals and communities to care for mental health—together.

More effective and affordable treatment strategies for Hepatitis C

Oxford University Clinical Research Unit (OUCRU) announced promising results from the VIETNARMS trial, a years-long multi-arm clinical trial conducted in Vietnam. The trial found that the readily available and affordable Hepatitis C treatment sofosbuvir/daclatasvir had a >95% cure rate. The results offer important insights into new treatment regimens for Hepatitis C, potentially reducing treatment durations and halving treatment costs.

Building Better Vaccines: Dr Thitinan Kitisin Explores Tonsil Organoids Models in Thailand

Years of groundwork have led Mahidol University Assistant Professor Dr Thitinan Kitisin to his first major step: leading an advanced vaccine research project in Thailand. With support from MODRA, he’s now developing one of the first tonsil organoid models in the country, a small but important step toward improving how vaccines are tested. Along the way, he’s also passing on practical research skills to the next generation of Thai scientists.

Professor Buddha Basnyat recognised by the Nepal Health Research Council

Professor Buddha Basnyat has received the NHRC Lifetime Achievement Award for Health Research in Nepal. The Nepal Health Research Council (NHRC) recently conferred its prestigious Lifetime Achievement Award for Health Research upon Professor Basnyat at the 11th National Summit of Health and Population Scientists. This honour recognises his exceptional contributions to medical research and public health over a career spanning more than five decades.

Blog: Tackling newborn infection risks in Nepal

At OUCRU Nepal, microbiologist Sulochana Manandhar spent much of her early career at the lab bench, examining bacteria, fine-tuning methods, and chasing answers to scientific questions. Now, with support from the MODRA programme, she’s leading her first hospital-based study, bringing new attention to neonatal health risks in Nepal.

Celebrate World Health Worker Week

The world is facing a shortage of 11 million health workers by 2030. World Health Worker Week calls for increased investment in all cadres of the health workforce - nurses, doctors, pharmacists, and others vital to resilient health systems. Health workers save lives, support economies, and advance development goals. Collaborative efforts, such as OUCRU’s training programme in Dak Lak, Vietnam, demonstrate the benefits of investment, with increased vaccine uptake. Protecting, valuing, and training health workers strengthens global health.

Blog: From post-PhD uncertainty to leading international research

Dr Duong Thi Hue Kien, a Post-doc Scientist at OUCRU, has shared her experience of finishing her PhD and kickstarting her career in science. She documents the highs and the lows, as well as how she was able to move forward in her career with support from the MORU–OUCRU Discovery Research Academy.

One-third of antibiotics used in Vietnam are ‘inappropriate’

Ranking 11th globally in antibiotic use, Vietnam faces a serious risk of drug resistance, ‘running out of treatment options due to antibiotic resistance’.

OUCRU Hosts Health Innovation and Entrepreneurship Training

OUCRU Ho Chi Minh City recently hosted a three-day Health Innovation and Entrepreneurship Training course. The course, organised by OUCRU and the UK’s Foreign and Commonwealth Development Office, welcomed 25 participants selected for their potential to drive innovation across diverse organisations, including non-profit, for-profit, social profit, and governmental bodies.

Tuberculous meningitis survivor: “TBM can be completely cured.”

Tuberculous meningitis (TBM) is a severe form of tuberculosis with high mortality and long-term disability risks, especially in children aged 1–5. It accounts for 1–5% of TB cases. WHO recommends a new 6-month treatment alternative to the traditional 12-month regimen. OUCRU is conducting a trial to assess its effectiveness. The project also addresses post-treatment support through a community advisory board and co-designed resources, aiming to improve care and outcomes for TBM-affected children and their families.

Recap: Southeast Asia Social, Ethical and Engagement Aspects of Pandemic Preparedness Workshop

From 18-19 February 2025, a workshop focusing on the social, ethical, and engagement aspects of pandemic preparedness took place in Da Nang, Vietnam. Thirty-one participants from five Southeast Asian countries attended, representing health research, academia, policy, community engagement, and local community organisations.

OUCRU Hosts Intensive Care Training for Healthcare Workers

OUCRU Ho Chi Minh recently concluded its annual three-day intensive care training program in Vietnam, made possible through the generous funding of Dragon Capital. Building upon the success of previous iterations, this year’s training aims to equip Vietnamese healthcare professionals with the latest advancements in intensive care management, particularly for life-threatening infectious diseases.

60% of hepatitis C patients do not know how they had the disease

A survey at Vietnam's National Hospital for Tropical Diseases found 60% of hepatitis C patients unaware of how they contracted the disease, often diagnosed late. Globally, viral hepatitis causes 3,500 daily deaths, ranking second among infectious killers after tuberculosis. Advances in treatment affordability and public health policies aim to improve outcomes. OUCRU's research explores cultural and psychological factors impacting diagnosis and care, supporting WHO's goal to eliminate hepatitis by 2030.

Researchers develop AI-powered tools to improve pneumonia care

A team of researchers at OUCRU was recently awarded a multi-million-dollar Discovery Award from the Wellcome Trust to develop AI tools to advance pneumonia research.

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