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Ashish Giri

Sonia Lewycka: One Health interventions to combat antimicrobial resistance

Antimicrobial resistance can be viewed through a One Health lens across humans, animals and the environment. Focussing on primary care, tests offered at point-of-care in Vietnam to curb antibiotic overuse yielded promising but nuanced results. The Just Transition initiative, examining justice implications of AMR policies globally, aims to align efforts with climate change mitigations for mutual benefits.

Sassy Molyneux: Strengthening health and research systems

Health systems in LMICs face daily stresses such as resource shortages and policy changes, alongside periodic shocks such as epidemics. Enhancing resilience combined with research ethics ensures high-quality research responsive to local communities. Minimising moral distress among frontline staff in international research is crucial for sustaining quality healthcare and advancing science amid challenging conditions.

Attakrit Leckcivilize: Physician Associates & the NHS workforce crisis

To improve health systems, workers and healthcare policy, we look at incentive motivation and human behaviour from an economist point of view. Currently, we're collaborating with the NHS to study Physician Associates, a newly regulated profession. Our research aims to address workforce challenges, emphasizing recruitment, retention, and development to improve care quality, recognizing the vital role of human connection in healthcare delivery.

Proochista Ariana: Building capacity for global health impact

The intersection between international developments and health is complex and multidimensional. Development initiatives, such as building roads, can enhance access to healthcare, education and markets, yet may also increase risks such as accidents and disease transmission. In Liberia, we investigate factors contributing to maternal and neonatal mortality through policy analysis and community perspectives. Our Master’s in International Health and Tropical Medicine aims to foster effective solutions and capacity building in global health leadership.

Jacob McKnight: Preparing Kenya’s health system for extreme weather

In both high- and low-income countries, health systems need to be ready for extreme weather. While sustainability efforts are underway, health systems must cope with events like floods and droughts, which increase healthcare demand and disrupt services. The NEWRISK project in Kenya addresses these challenges, emphasizing resilience and insurance strategies to maintain healthcare access during crises, amid climate change's broad impacts on health systems.

Sebastian Fuller: Implications of new technologies in healthcare

New healthcare technologies, in our case sexually transmitted infections diagnostics, need to be integrated with all stakeholders, including the WHO. In countries like Malta and Zambia, we explore scalable implementation and antimicrobial resistance issues. Expanding diagnostics enhances treatment accuracy by reducing reliance on syndromic approaches. Reducing antibiotic resistance is a crucial element in evolving global health systems.

Yingxi Zhao: Medical workforce research in Kenya

The issue of global health workforce shortage is especially acute in low- and middle-income countries like Kenya. These countries face urban concentration of workers, migration to high-income countries, poor training and burnout, all of which impacts care quality. Addressing these issues through ethical recruitment, developing roles and improving workforce well-being is crucial for effective healthcare systems and public resource management.

Alun Davies: Engaging communities for ethical research

The Global Health Network supports researchers in global health with resources and a community of one million practitioners. Mesh, TGHN platform for community engagement, is offering an online training course for community engagement and involvement in health research. Ensuring that community members are involved in all steps of the research process has become vital, enhancing both ethics and scientific rigour, and improving research practices and policy influence.

Caesar Atuire: Making health more ethical for all

Ethics emphasises fair and equitable actions, particularly important in healthcare. For example, a project on solidarity highlights disparities in COVID-19 vaccine distribution, questioning ethical ideals. Major challenges include health inequalities, radical disagreements, AI responsibility and structural injustice. Our research looks at justice and equity in health interventions, ensuring they reach those in need effectively and timely.

Philippe Guérin: Enabling data reuse to combat infectious diseases

IDDO is a data platform that facilitates the integration and analysis of individual patient data from diverse studies, uncovering new insights otherwise inaccessible. Through meticulous curation and merging of data, IDDO unearth crucial evidence, such as the impact of malaria treatment on malnourished children, a group usually excluded from trials. This comprehensive approach not only informs better treatment strategies but also identifies gaps in current knowledge, guiding future research directions and potentially transforming healthcare guidelines worldwide.

Susanna Dunachie: Vaccines for vulnerable populations

Focussing on vaccines for vulnerable populations, the Tropical Immunology Research Group study immune responses in healthy individuals to understand how to protect those with frail immune systems, such as the elderly and diabetics, from bacterial infections like E. coli and Klebsiella. Key goals include identifying immune markers of protection and designing vaccines to prevent deaths in low- and middle-income countries. Addressing antimicrobial resistance is urgent to prevent untreatable future infections.

Celine Caillet: Detecting substandard and falsified medical products

The Medicine Quality Research Group focuses on substandard and falsified medicines, critical issues often overlooked in LMICs. Recent tragic incidents underscore the urgent need for better regulatory oversight. The group explores portable screening technologies to empower regulators in identifying and preventing such medicines, potentially mitigating widespread harm and economic strain on health systems.

Fernando Rubinstein: Helping to build research capacity

The Global Health Network aims to enhance research capacity in LMICs where formal research training is not accessible, by offering free open access training materials, overcoming barriers like cost and geography. Challenges include securing sustained funding to maintain equitable access to essential training, crucial for empowering local research communities and addressing regional health priorities.

Trudie Lang: The Global Health Network, Driving equity in health research

The Global Health Network is a global community connecting health researchers and organisations to overcome research barriers across diseases and locations. It provides access to knowledge, training and resources, empowering researchers, especially in low-resource areas, to conduct high-quality research. Our goal is to shift the research hierarchy, enabling all healthcare workers to engage in impactful, pragmatic studies. This approach addresses the need for comprehensive research ecosystems to improve healthcare outcomes.

Mike English: Hospitals and Health for All?

Health Systems Collaborative focuses on improving healthcare delivery for low-income populations in Africa, especially in hospitals in rural areas. The AFRHiCARE project, a collaboration with clinicians, social scientists, and economists in Uganda, Kenya, South Africa and Oxford, examines how hospitals can effectively utilise technologies and innovations. We aim to optimise hospital operations to deliver high-quality care, ensuring essential services for patients in resource-poor settings across Africa.

Ben Cooper: Drug-resistant infections and disease dynamics

Infectious diseases carry a huge impact and developing interventions remains a priority. A recent trial in Southeast Asia aimed at shortening antibiotic treatment for ventilator-associated pneumonia, reducing side effects and the risk of antimicrobial resistance. Collaborations underline the global AMR burden and the need for effective solutions, from improved antibiotics use to novel diagnostics and vaccines, crucial amid rising challenges.

Arancha de la Horra: Nurses in Research

Global Research Nurses support nurses and midwives from LMICs to lead research through capacity-building workshops and small grants across Africa, Asia, and Latin America. For instance, workshops enhance qualitative research skills in proposal development, data collection, and manuscript writing, resulting in impactful research projects. Despite challenges like awareness and under-representation, empowering nurses and midwives in research not only enhances healthcare decision-making, but also fosters career growth and improves patient-focused care globally. Global Research Nurses is a group of The Global Health Network.

Raph Hamers: Infectious diseases research in Indonesia

Infectious diseases research at OUCRU Indonesia addresses prevention, diagnosis and management, focusing on tuberculosis, HIV, COVID-19 and antimicrobial resistance. Participation in the RECOVERY trial contributed to the identification of four treatments for severe COVID-19. Challenges include the need of more research expertise and translating findings into policy. Our goal is to reduce disease burdens through technical and implementation innovations.

Sophie Yacoub: Dengue research in Vietnam

Dengue is a global health concern exacerbated by urbanisation and climate change. OUCRU research themes include improving patient monitoring with wearable devices and clinical decision support systems, conducting clinical trials for therapeutics, assessing climate change's impact, and studying immune responses in high-risk groups. Our goal is to enhance early prediction and treatment strategies to improve patient care and health system efficiency.