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The RECOVERY trial was established in March as a randomised clinical trial to test a range of potential treatments for COVID-19, including lopinavir-ritonavir, an antiviral treatment commonly used to treat HIV. There was no significant difference in the primary endpoint of 28-day mortality, and the results were consistent in different subgroups of patients. There was also no evidence of beneficial effects on the risk of progression to mechanical ventilation or length of hospital stay. The trial Steering Committee concluded that there is no beneficial effect of lopinavir-ritonavir in patients hospitalised with COVID-19 and closed that treatment arm.
Arjen Dondorp
Principal Investigators Research Scientists
Arjen Dondorp - Professor of Tropical Medicine
Trudie Lang
Principal Investigators Research Scientists
Trudie Lang - Professor of Global Health Research
Eduard Sanders
Principal Investigators Research Scientists
Eduard Sanders - Professor of global health practice
Nicholas White
Principal Investigators Research Scientists
FRS Nicholas White - Professor of Tropical Medicine
Paul Newton
Principal Investigators Research Scientists
Paul Newton - Professor of Tropical Medicine
Wirichada Pan-ngum
MSc IHTM Lecturers MSc MGH Lecturers Research Scientists
Wirichada Pan-ngum - Associate Professor
Louise Thwaites
Principal Investigators Research Scientists
BSc MBBS MRCP MD DMSMed MLCOM Louise Thwaites - Associate Professor
Raph Hamers
Principal Investigators Research Scientists
MD PhD Raph Hamers - Associate Professor in Infectious Diseases
Yoel Lubell
MSc IHTM Lecturers Principal Investigators Research Scientists
Yoel Lubell - Professor of Global Health
Mayfong Mayxay
Research Scientists
Mayfong Mayxay - Vice-President of the Lao University of Health Sciences, Ministry of Health
Nicholas Day
MSc IHTM steering committee Principal Investigators Research Scientists
MA BM BCh DM FRCP FMedSci Nicholas Day - Professor of Tropical Medicine
James Berkley
MSc IHTM Lecturers Principal Investigators Research Scientists
MBBS MTropMed MRCP MD FRCPCH FMedSci James Berkley - Professor of Paediatric Infectious Diseases