Professor C Louise Thwaites
Contact information
Websites
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VITAL project
The VITAL project aims to reduce morbidity and mortality from infectious diseases in Asia by using innovative technology and clinical approaches
Publications
Louise has published more than 50 articles in international journals.
Research groups
Louise Thwaites
BSc MBBS MRCP MD DMSMed MLCOM
Associate Professor
- Senior Clinical Research Fellow
Emerging Infection
Louise Thwaites is a clinical researcher and member of the Emerging Infections group at OUCRU. She is an associate professor in the Centre for Tropical Medicine and Global Health at the University of Oxford and an honorary consultant at Oxford University Hospitals Trust.
Her research focuses on the care of critically ill patients in resource-restricted settings and she has spent much of her career engaged in research into tetanus. This includes conducting a large randomized controlled trials of magnesium sulphate and intrathecal tetanus antitoxin in tetanus, investigation into the underlying pathophysiology and long-term outcome following tetanus and, trying to understand which populations are most at risk of tetanus and ways to improve vaccination uptake these communities. More broadly, she is interested in ways of improving care of critically ill patients using new technologies and forging new collaborations to achieve this. Her current role in the VITAL project involves developing new devices and technologies for use in diagnosis, treatment and rehabilitation following diseases such as tetanus, sepsis and dengue.
Louise is an expert consultant to the World Health Organization. She is a member of the Crit Care Asia network and leads the guidelines and policy working group of the Asia Pacific Sepsis Association as well as being a member of the sepsis in resource-limited settings–expert consensus recommendations group of the European Society of Intensive Care Medicine and the Mahidol-Oxford Research Unit.
Key publications
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Heart Rate Variability as an Indicator of Autonomic Nervous System Disturbance in Tetanus.
Duong HTH. et al, (2020), The American journal of tropical medicine and hygiene, 102, 403 - 407
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Functional outcome and muscle wasting in adults with tetanus.
Trung TN. et al, (2019), Transactions of the Royal Society of Tropical Medicine and Hygiene
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Increasing women's leadership in science in Ho Chi Minh City.
Hoa NT. et al, (2019), Lancet (London, England), 393, 523 - 524
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Recommendations for infection management in patients with sepsis and septic shock in resource-limited settings
Thwaites CL. et al, (2016), Intensive Care Medicine, 42, 2040 - 2042
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Tetanus (vol 393, pg 1657, 2019)
Yen LM. and Thwaites CL., (2019), LANCET, 393, 1698 - 1698
Recent publications
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Epidemiological Characteristics, Ventilator Management, and Clinical Outcome in Patients Receiving Invasive Ventilation in Intensive Care Units from 10 Asian Middle-Income Countries (PRoVENT-iMiC): An International, Multicenter, Prospective Study
Pisani L. et al, (2021), The American Journal of Tropical Medicine and Hygiene
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The Natural History and Transmission Potential of Asymptomatic Severe Acute Respiratory Syndrome Coronavirus 2 Infection
Van Vinh Chau N. et al, (2020), Clinical Infectious Diseases, 71, 2679 - 2687
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Establishing a critical care network in Asia to improve care for critically ill patients in low- and middle-income countries
(2020), Critical Care, 24
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Purchase and use of antimicrobials in the hospital sector of Vietnam, a lower middle-income country with an emerging pharmaceuticals market
Dat VQ. et al, (2020), PLOS ONE, 15, e0240830 - e0240830
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Clinical, etiological and epidemiological investigations of hand, foot and mouth disease in southern Vietnam during 2015 - 2018.
Nhan LNT. et al, (2020), PLoS neglected tropical diseases, 14