Professor Sir Nicholas J White
Podcast interview
Artemisinin therapy for malaria
Malaria kills more than half a million people every year. Following a number of groundbreaking clinical trials, Professor Sir Nick White and his Thailand team successfully demonstrated the effectiveness of artemisinin drug therapy for malaria in adults, children and infants. He also pioneered artemisinin combination therapy, the first-line treatment for malaria worldwide.
Research groups
Colleges
Nicholas White
FRS
Professor of Tropical Medicine
- Professor at Mahidol University in Thailand
Professor White’s diverse interests include the epidemiology, pathophysiology and management of uncomplicated and severe malaria, meliodosis, enteric fever, tetanus, dengue haemorrhagic fever, Japanese encephalitis and tuberculosis. His particular interests at present include the pathophysiology and treatment of severe malaria, the prevention of antimalarial drug resistance using artemisinin-based combinations. and the biology of relapse in vivax malaria.
Vivax malaria
Recent publications
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Methaemoglobinaemia and the radical curative efficacy of 8-aminoquinoline antimalarials.
White NJ. et al, (2022), British journal of clinical pharmacology
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Methaemoglobinaemia and the radical curative efficacy of 8-aminoquinoline antimalarials
White N. et al, (2021)
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Clustering of malaria in households in the Greater Mekong Subregion: operational implications for reactive case detection
Mukaka M. et al, (2021), Malaria Journal, 20
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Development of weight and age-based dosing of daily primaquine for radical cure of vivax malaria
Taylor WR. et al, (2021), Malaria Journal, 20
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Falciparum but not vivax malaria increases the risk of hypertensive disorders of pregnancy in women followed prospectively from the first trimester
Harrington WE. et al, (2021), BMC Medicine, 19