Professor Sir Nicholas J White
Podcast interview
Artemisinin therapy for malaria
Malaria kills more than half a million people every year. Following a number of groundbreaking clinical trials, Professor Sir Nick White and his Thailand team successfully demonstrated the effectiveness of artemisinin drug therapy for malaria in adults, children and infants. He also pioneered artemisinin combination therapy, the first-line treatment for malaria worldwide.
Research groups
Colleges
Nicholas White
FRS
Professor of Tropical Medicine
- Professor at Mahidol University in Thailand
Professor White’s diverse interests include the epidemiology, pathophysiology and management of uncomplicated and severe malaria, meliodosis, enteric fever, tetanus, dengue haemorrhagic fever, Japanese encephalitis and tuberculosis. His particular interests at present include the pathophysiology and treatment of severe malaria, the prevention of antimalarial drug resistance using artemisinin-based combinations. and the biology of relapse in vivax malaria.
Vivax malaria
Recent publications
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Substantial misdiagnosis of severe malaria in African children.
White NJ. et al, (2022), Lancet, 400
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Improving the diagnosis of severe malaria in African children using platelet counts and plasma Pf HRP2 concentrations
Watson JA. et al, (2022), Science Translational Medicine, 14
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Definitions matter: Heterogeneity of COVID-19 disease severity criteria and incomplete reporting compromise meta-analysis
Guérin PJ. et al, (2022), PLOS Global Public Health, 2, e0000561 - e0000561
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Stopping prereferral rectal artesunate - a grave error.
Watson JA. et al, (2022), BMJ Glob Health, 7
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The impact of malaria-protective red blood cell polymorphisms on parasite biomass in children with severe Plasmodium falciparum malaria.
Uyoga S. et al, (2022), Nature communications, 13