Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.
Skip to main content

Professor Trudie Lang

Professor Trudie Lang

Podcast interview

The Global Health Network is a successful and growing online science park comprised of varied research communities for different health research groups and cross-cutting health topics. It is built for the research and wider health community by researchers and public health practitioners themselves. It is a trusted source of quality information, education and research tools.

Trudie Lang

Professor of Global Health Research

  • Head of The Global Health Network, @Oxford

The Global Health Network

The Global Health Network accelerates and streamlines research through an innovative digital community, facilitating collaboration and resource sharing across global health


Clinical research brings evidence base for prevention and treatment of disease and is critically important in the field of Global Health. This importance is threefold: there is the greatest potential for improving health in numerical terms, there is enormous potential gain from relatively simple interventions, and developing countries have been under represented in clinical studies to date.
Clinical trials in developing countries typically have endpoints that are severe disease outcomes or mortality. They more often involve children and are sponsored by not-for-profit organisations. There are also specific situations that merit more and better clinical trials to inform policy such as disease outbreaks, including those with pandemic potential, in displaced populations, refugee camps and natural disasters. These very specialist situations and environments need a research focus in order to identify highly practical and appropriate interpretation of guidelines and regulations to enable rapid and flexible trial implementation whilst maintaining the same degree of attention to ethical standards and to quality of processes and data as any international trial. 
There is a high level of activity with externally sponsored product development trials. However disease management trials are equally important and product development trials alone do not leave sites with the ability to run their own broad programmes. To encourage more locally led trials we need to support researchers and provide skills and guidance in setting questions and operating protocols.


We have established a dedicated and collaborative online science park. Global Health Network is a one-stop shop for sharing research methods and facilitating collaboration among global health professionals to fuel faster and better evidence to improve health in resource-limited settings.

One of the areas within The Global Health Network is a cross-cutting resource called Global Health Trials which is a forum to help clinical researchers with trial operations, design, methods and interpretation of regulations. Global Health Trials offers guidance whilst also identifying problems and potential solutions and encouraging the sharing of best practices. Using a participatory mixed methods action research approach we are conducting methodology research to identify the real barriers and issues. The data gathered is being used to continuously update the web forum and to develop resources and guidance to enable the conduct of clinical trials to be both appealing and straightforward.

The main objective of this research is to identify where the interpretation of GCP and other regulatory requirements is problematic in resource poor settings and quantify the impact these issues are having. The identification of the problems will lead to studies that will generate new tools that will be made available on the web forum. This is a continuous iterative process so continuing the theme of participatory action research, with the web forum providing the open-access, open source and fully collaborative vehicle.

There is a need for well trained and qualified clinical trialists to lead and design their own trial programmes in developing countries in order to catch up with the career structures in the west. Therefore another aim of this collaboration is to develop training courses and resources to meet specific gaps. At present there are diplomas and MSc clinical trial courses that are taught and available through distance learning. Whilst these are good, they are focused on industry and US/European regulatory needs. Our research will also help to guide the design and content of courses specifically focused on developing country clinical trials based on what we have shown to work locally in vulnerable populations.
Our findings will also enable funders interested in capacity building to direct their resources appropriately and product developers to select trial sites. Although we are focusing our research on tropical medicine we expect some of our findings to be generally applicable to anyone engaged in non-commercial trials.

Key publications

Recent publications

More publications