Professor Nicholas PJ Day
Podcast interview
Infectious diseases in South East Asia
MORU aims to fight the infectious tropical diseases affecting rural communities in Asia and elsewhere in the developing world. MORU's malaria research aims to directly improve the treatment of the disease globally. It's researchers focus on the treatment of severe malaria, the spread of antimalarial drug resistance, and the pathophysiology of falciparum and vivax malaria. These studies are used to formulate novel adjuvant therapies, and have been translated into recommendations for the use of artemisinin based combination therapies.
Research groups
Colleges
Nicholas Day
MA BM BCh DM FRCP FMedSci
Professor of Tropical Medicine
- Director of the Mahidol Oxford Tropical Medicine Research Unit, Thailand, and of the Wellcome Trust Thailand Asia and Africa Programme
MORU
Nick Day's interests include the epidemiology, diagnosis, pathophysiology, pathogen biology, treatment and prevention of malaria, rickettsial diseases including scrub typhus, melioidosis, leptospirosis, rickettsial infections, influenza, dengue and other communicable diseases afflicting rural populations throughout Asia and beyond. Cross-cutting interests include the drivers and epidemiology of AMR, and the syndromic management of febrile illnesses and sepsis in LMIC settings.
Recent publications
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Malaria outbreak in Laos driven by a selective sweep for Plasmodium falciparum kelch13 R539T mutants: a genetic epidemiology analysis
Wasakul V. et al, (2023), The Lancet Infectious Diseases, 23, 568 - 577
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Cost, health impacts and cost effectiveness of iceless refrigeration in India's last-mile vaccine cold chain delivery
Plewes K. et al, (2023), Transactions of The Royal Society of Tropical Medicine and Hygiene, 117, 310 - 312
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Correction: A time-course comparative clinical and immune response evaluation study between the human pathogenic Orientia tsutsugamushi strains: Karp and Gilliam in a rhesus macaque (Macaca mulatta) model.
Inthawong M. et al, (2023), PLoS neglected tropical diseases, 17
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Safety of age-dosed, single low-dose primaquine in children with glucose-6-phosphate dehydrogenase deficiency who are infected with Plasmodium falciparum in Uganda and the Democratic Republic of the Congo: a randomised, double-blind, placebo-controlled, non-inferiority trial
Taylor WR. et al, (2023), The Lancet Infectious Diseases, 23, 471 - 483
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Lineage-informative microhaplotypes for spatio-temporal surveillance of Plasmodium vivax malaria parasites.
Siegel SV. et al, (2023), medRxiv