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Research Highlights

  • Dengue virus induces PCSK9 expression to alter antiviral responses and disease outcomes

    Posted 06/08/2020. Cholesterol is required for efficient dengue virus (DENV) replication, however statin treatment did not show efficacy against dengue in clinical trials, and underscored the need for a more detailed understanding of the interaction between DENV and cellular cholesterol. In this paper, in collaboration with DUKE-NUS, Sophie Yacoub and colleagues demonstrate the pivotal role of PCSK9 in DENV infections.

  • Addressing challenges for clinical research responses to emerging epidemics and pandemics

    Posted 04/08/2020. Major infectious disease outbreaks are a constant threat to human health; clinical research responses generate evidence to improve outcomes and outbreak control. Experiences from previous epidemics have identified multiple challenges to undertaking timely clinical research responses to emergency epidemics. Louise Sigfrid and colleagues review those challenges and identify solutions to address them.

  • Evaluation of the forum theatre approach for public engagement around antibiotic use in Myanmar

    Posted 31/07/2020. Myo Maung Maung Swe and colleagues describe evaluation and experience of using the forum theatre technique, a novel form of public engagement. Our experience was fun, informative and encouraged widespread participation around the subject of antibiotic use. We believe that this technique will be of great interest to scientists who engage in activities using participatory techniques.

More research highlights

Global Research for a Global Pandemic

TGHN audio film how we can implement research during the COVID-19 pandemic, to combat the disease and for future outbreaks.

MSc International Health and Tropical Medicine

The MSc in International Health and Tropical Medicine provides a multidisciplinary and interdisciplinary foundation in global health. This course embraces the breadth and complexity of global health challenges facing resource limited contexts and equips candidates with the tools and awareness to contribute to innovative solutions.

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COVID outbreak

During the COVID-19 pandemic, the Centre for Tropical Medicine and Global Health is taking measures to prevent the spread of the disease.

Departments are instructed by the University’s Registrar to continue to work from home where possible, and manage the return to on site working, based on the University guidelines for risk assessments and work prioritisation.

This is to restrict contact between individuals as far as possible. The University remains open and operating as far as possible with the following restrictions:

  • No public access to the University
  • On-site activity permitted where it cannot be undertaken remotely, driven by safety, capacity and other factors such as schools reopening/other changes in government guidelines
  • Teaching and assessment are undertaken remotely where possible and, depending on government guidelines, gatherings of staff and students only permitted where essential for teaching and assessment to take place