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During the 2013-2016 Ebola outbreak in West Africa an expert panel was established on the instructions of the UK Prime Minister to identify priority pathogens for outbreak diseases that had the potential to cause future epidemics. A total of 13 priority pathogens were identified, which led to the prioritisation of spending in emerging diseases vaccine research and development from the UK. This meeting report summarises the process used to develop the UK pathogen priority list, compares it to lists generated by other organisations (World Health Organisation, National Institutes of Allergy and Infectious Diseases) and summarises clinical progress towards the development of vaccines against priority diseases. There is clear technical progress towards the development of vaccines. However, the availability of these vaccines will be dependent on sustained funding for clinical trials and the preparation of clinically acceptable manufactured material during inter-epidemic periods.

Original publication

DOI

10.1016/j.vaccine.2019.09.009

Type

Publication Date

10/2019

Volume

37

Pages

6241 - 6247

Addresses

Pathobiology and Population Science, The Royal Veterinary College, Hawkshead Lane, Hatfield AL9 7TA, UK. Electronic address: rnoad@rvc.ac.uk.

Keywords

Humans, Communicable Diseases, Communicable Diseases, Emerging, Hemorrhagic Fever, Ebola, Vaccines, Ebola Vaccines, Communicable Disease Control, Biomedical Research, National Institutes of Health (U.S.), World Health Organization, Africa, Western, United States, Congresses as Topic, Epidemics, United Kingdom