Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Healthcare workers (n = 803) with mild symptoms were tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (n = 90 positive) and asked to complete a symptom questionnaire. Anosmia, muscle ache, ocular pain, general malaise, headache, extreme tiredness and fever were associated with positivity. A predictive model based on these symptoms showed moderate discriminative value (sensitivity: 91.2%; specificity: 55.6%). While our models would not justify presumptive SARS-CoV-2 diagnosis without molecular confirmation, it can contribute to targeted screening strategies.

Original publication





Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

Publication Date





Department of Medical Microbiology, Radboud Centre for Infectious Diseases, Radboud university medical centre, Nijmegen, The Netherlands.


Humans, Pneumonia, Viral, Coronavirus Infections, Pharyngitis, Cough, Headache, Fever, Fatigue, Patient Isolation, Cohort Studies, Predictive Value of Tests, Health Policy, Adult, Aged, Middle Aged, Health Personnel, Personnel, Hospital, Netherlands, Young Adult, Eye Pain, Pandemics, Myalgia, Betacoronavirus, COVID-19, SARS-CoV-2