Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

People with HIV (PWH) have a >2-fold greater risk for development of cardiovascular disease (CVD), which may be associated with abnormalities in 24-h ambulatory blood pressure measurement (ABPM) profile. We conducted a nested case-control study of ABPM in 137 PWH and HIV-uninfected controls with normal and high clinic blood pressure (BP) in Tanzania. Nocturnal non-dipping of heart rate (HR) was significantly more common among PWH than HIV-uninfected controls (p = .01). Nocturnal non-dipping of BP was significantly more common in PWH with normal clinic BP (p = .048). Clinical correlates of nocturnal non-dipping were similar in PWH and HIV-uninfected adults and included higher BMI, higher CD4+ cell count, and high C-reactive protein for HR and markers of renal disease for BP. In conclusion, nocturnal non-dipping of both BP and HR was more common in PWH but further research is needed to determine causes and consequences of this difference.

Original publication

DOI

10.1111/jch.14300

Type

Journal

Journal of clinical hypertension (Greenwich, Conn.)

Publication Date

07/2021

Volume

23

Pages

1452 - 1456

Addresses

Center for Global Health, Weill Cornell Medicine, New York, NY, USA.

Keywords

Humans, HIV Infections, Hypertension, Blood Pressure Monitoring, Ambulatory, Case-Control Studies, Circadian Rhythm, Blood Pressure, Heart Rate, Adult, Tanzania