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Plasmodium falciparum artemisinin resistance (ART-R) may have evolved independently in various areas of the Greater Mekong Sub-region (1, 2), prompting the World Health Organization to change its regional policy from containment to elimination (3). Risks associated with ART-R include compromised use of artemisinin combined therapy (ACT), partner drug resistance selection, total ART-R resistance and geographical extension to other malaria endemic regions (2, 3). We therefore need to characterize ART-R in each independent setting and rapidly update the list of ART-R makers.

Type

Journal

Emerging Infectious Diseases journal

Publisher

Centre for Disease Control

Publication Date

01/05/2016

Keywords

parasite clearance half-life, malaria, K13, Ring-stage Survival Assay, Plasmodium falciparum, Thai-Myanmar border, artemisinin resistance