Headway made towards biosignatures for incipient tuberculosis
Simon Mendelsohn (cohort 2015-16), Thomas J Scriba,
Identification of individuals with tuberculosis for antibiotic treatment is a major component of the of WHO's End TB Strategy. Diagnostic tests for tuberculosis rely on detection of Mycobacterium tuberculosis in sputum expectorated by a person with productive cough. The search for new sputum-independent diagnostic tests is gaining momentum, as exemplified by advances in urine-based point-of-care lipoarabinomannan lateral flow assays for use in hospitalised patients with HIV.