Recent publications by Researchers affiliated with the Centre for Tropical Medicine and Global Health
Distinct transcriptomic signatures define febrile malaria depending on initial infective states, asymptomatic or uninfected.
Kimenyi KM. et al, (2024), BMC infectious diseases, 24
Extracellular vesicles could be a putative posttranscriptional regulatory mechanism that shapes intracellular RNA levels in Plasmodium falciparum.
Kioko M. et al, (2023), Nature communications, 14
Kinetics of naturally induced binding and neutralising anti-SARS-CoV-2 antibody levels and potencies among SARS-CoV-2 infected Kenyans with diverse grades of COVID-19 severity: an observational study
Kimotho J. et al, (2023), Wellcome Open Research, 8, 350 - 350
From contigs towards chromosomes: automatic improvement of long read assemblies (ILRA).
Ruiz JL. et al, (2023), Briefings in bioinformatics, 24
The Dantu blood group prevents parasite growth in vivo: Evidence from a controlled human malaria infection study.
Kariuki SN. et al, (2023), eLife, 12
Plasmodium falciparum adapts its investment into replication versus transmission according to the host environment.
Abdi AI. et al, (2023), eLife, 12
Anti-merozoite antibodies induce natural killer cell effector function and are associated with immunity against malaria.
Odera DO. et al, (2023), Science translational medicine, 15
A pragmatic randomized controlled trial of standard care versus steroids plus standard care for treatment of pneumonia in adults admitted to Kenyan hospitals (SONIA)
Lucinde R. et al, (2022), Wellcome Open Research, 7, 269 - 269
Spatio-temporal distribution of antimalarial drug resistant gene mutations in a Plasmodium falciparum parasite population from Kilifi, Kenya: A 25-year retrospective study
Omedo I. et al, (2022), Wellcome Open Research, 7, 45 - 45
Impact of Plasmodium falciparum small-sized extracellular vesicles on host peripheral blood mononuclear cells
Mwangi SJ. et al, (2021), Wellcome Open Research, 5, 197 - 197
Extracellular vesicles isolated from milk can improve gut barrier dysfunction induced by malnutrition.
Maghraby MK. et al, (2021), Scientific reports, 11
Impact of Plasmodium falciparum small-sized extracellular vesicles on host peripheral blood mononuclear cells
Mwangi SJ. et al, (2020), Wellcome Open Research, 5, 197 - 197
No evidence of P. falciparum K13 artemisinin conferring mutations over a 24-year analysis in Coastal Kenya, but a near complete reversion to chloroquine wild type parasites.
Wamae K. et al, (2019), Antimicrobial agents and chemotherapy, 63, AAC.01067 - AAC.01019
Antigenic cartography of immune responses to Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1).
Tuju J. et al, (2019), PLoS pathogens, 15
Exploring Plasmodium falciparum Var Gene Expression to Assess Host Selection Pressure on Parasites During Infancy.
Kivisi CA. et al, (2019), Frontiers in immunology, 10
Long read assemblies of geographically dispersed Plasmodium falciparum isolates reveal highly structured subtelomeres
Otto TD. et al, (2018), Wellcome Open Research, 3, 52 - 52
Controlled Human Malaria Infection in Semi-Immune Kenyan Adults (CHMI-SIKA): a study protocol to investigate in vivo Plasmodium falciparum malaria parasite growth in the context of pre-existing immunity.
Kapulu MC. et al, (2018), Wellcome open research, 3
Plasmodium falciparum malaria parasite var gene expression is modified by host antibodies: longitudinal evidence from controlled infections of Kenyan adults with varying natural exposure
Abdi AI. et al, (2017), BMC Infectious Diseases, 17
Proteomic analysis of extracellular vesicles from a Plasmodium falciparum Kenyan clinical isolate defines a core parasite secretome
Abdi A. et al, (2017), Wellcome Open Research, 2, 50 - 50
Public antibodies to malaria antigens generated by two LAIR1 insertion modalities
Pieper K. et al, (2017), Nature, 548, 597 - 601