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Recent publications by Researchers affiliated with the Centre for Tropical Medicine and Global Health

In Silico Fragment-Based Design Identifies Subfamily B1 Metallo-β-lactamase Inhibitors

Journal article

Cain R. et al, (2018), Journal of Medicinal Chemistry, 61, 1255 - 1260

19 F-NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the São Paulo Metallo-β-Lactamase

Journal article

Abboud MI. et al, (2017), Angewandte Chemie International Edition, 56, 3862 - 3866

“To Cross-Seed or Not To Cross-Seed”: A Pilot Study Using Metallo-β-lactamases

Journal article

Abuhammad A. et al, (2017), Crystal Growth & Design, 17, 913 - 924

Comparison of Verona Integron-Borne Metallo-β-Lactamase (VIM) Variants Reveals Differences in Stability and Inhibition Profiles

Journal article

Makena A. et al, (2016), Antimicrobial Agents and Chemotherapy, 60, 1377 - 1384

Biochemical characterization of New Delhi metallo-β-lactamase variants reveals differences in protein stability

Journal article

Makena A. et al, (2015), Journal of Antimicrobial Chemotherapy, 70, 463 - 469

Monitoring Conformational Changes in the NDM-1 Metallo-β-lactamase by19F NMR Spectroscopy

Journal article

Rydzik AM. et al, (2014), Angewandte Chemie International Edition, 53, 3129 - 3133

Chromophore-Linked Substrate (CLS405): Probing Metallo-β-Lactamase Activity and Inhibition

Journal article

Makena A. et al, (2013), ChemMedChem, 8, 1923 - 1929