Recent publications by Researchers affiliated with the Centre for Tropical Medicine and Global Health
Robotic Mouse
Bitoun E. et al, (2021), Handbook of the Cerebellum and Cerebellar Disorders: Second Edition: Volume 3, 1667 - 1684
ZCWPW1 is recruited to recombination hotspots by PRDM9 and is essential for meiotic double strand break repair
Wells D. et al, (2020), eLife, 9
A high-resolution map of non-crossover events reveals impacts of genetic diversity on mammalian meiotic recombination.
Li R. et al, (2019), Nature communications
A high-resolution map of non-crossover events reveals impacts of genetic diversity on mammalian meiotic recombination
Li R. et al, (2019), Nature Communications, 10
Genetic diversity and its unexpected impacts on recombination, genome evolution, speciation and sterility in mammals
Li R. et al, (2019), EUROPEAN JOURNAL OF HUMAN GENETICS, 27, 1073 - 1073
A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis
Altemose N. et al, (2017), eLife, 6
Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice
Davies B. et al, (2016), Nature, 530, 171 - 176
A Novel Mouse Model of a Patient Mucolipidosis II Mutation Recapitulates Disease Pathology
Paton L. et al, (2014), Journal of Biological Chemistry, 289, 26709 - 26721
Robotic Mouse
Bitoun E. et al, (2013), Handbook of the Cerebellum and Cerebellar Disorders, 1481 - 1497
Oxr1 Is Essential for Protection against Oxidative Stress-Induced Neurodegeneration
Oliver PL. et al, (2011), PLoS Genetics, 7, e1002338 - e1002338
AF4 Is a Critical Regulator of the IGF-1 Signaling Pathway during Purkinje Cell Development
Bitoun E. et al, (2009), The Journal of Neuroscience, 29, 15366 - 15374
The Robotic Mouse: Understanding the Role of AF4, a Cofactor of Transcriptional Elongation and Chromatin Remodelling, in Purkinje Cell Function
Bitoun E. and Davies KE., (2009), The Cerebellum, 8, 175 - 183
The protein phosphatase PP2A-B′ subunit Widerborst is a negative regulator of cytoplasmic activated Akt and lipid metabolism inDrosophila
Vereshchagina N. et al, (2008), Journal of Cell Science, 121, 3383 - 3392
Comparative genetic analysis: the utility of mouse genetic systems for studying human monogenic disease
Oliver PL. et al, (2007), Mammalian Genome, 18
Keratitis?ichthyosis?deafness syndrome: disease expression and spectrum of connexin 26 (GJB2) mutations in 14 patients
Mazereeuw-Hautier J. et al, (2007), British Journal of Dermatology, 156, 1015 - 1019