Recent publications by Researchers affiliated with the Centre for Tropical Medicine and Global Health
Transitions in lineage specification and gene regulatory networks in hematopoietic stem/progenitor cells over human development
Roy A. et al, (2021), Cell Reports, 36, 109698 - 109698
Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia
Louka E. et al, (2021), Journal of Experimental Medicine, 218
Spliceosome mutations are common in persons with myeloproliferative neoplasm-associated myelofibrosis with RBC-transfusion-dependence and correlate with response to pomalidomide
Chowdhury O. et al, (2020), Leukemia, 35, 1197 - 1202
Rapid Emergence of Chronic Lymphocytic Leukemia During JAK2 Inhibitor Therapy in a Patient With Myelofibrosis
Sousos N. et al, (2020), HemaSphere, 4, e356 - e356
H3K79me2/3 controls enhancer–promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells
Godfrey L. et al, (2020), Leukemia
Trisomy 21 Driven Pro-Inflammatory Signalling in Fetal Bone Marrow May Play a Role in Perturbed B-Lymphopoiesis and Acute Lymphoblastic Leukemia of Down Syndrome
O'Byrne SI. et al, (2019), Blood, 134, 1206 - 1206
Discovery of a CD10 negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs.
O'Byrne S. et al, (2019), Blood
PF153 MLL-AF4 CAUSES ABERRANT UPREGULATION OF PROM1 (CD133) IN ACUTE LYMPHOBLASTIC LEUKEMIA BY CONTROLLING ENHANCER-PROMOTER INTERACTIONS
Godfrey L. et al, (2019), HemaSphere, 3, 29 - 29
Unravelling Intratumoral Heterogeneity through High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing
Rodriguez-Meira A. et al, (2019), Molecular Cell, 73, 1292 - 1305.e8
Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia
Louka E. et al, (2019)
Spliceosome Mutations Are Common in MPN-Associated Myelofibrosis with RBC-Transfusion-Dependence and Correlate with Response to Pomalidomide
Chowdhury O. et al, (2018), BLOOD, 132
Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls
Flannick J. et al, (2018), Scientific Data, 5, 180002 - 180002
Unraveling intratumoral heterogeneity through high-sensitivity single-cell mutational analysis and parallel RNA-sequencing
Rodriguez-Meira A. et al, (2018)
Sequence data and association statistics from 12,940 type 2 diabetes cases and controls
Jason F. et al, (2017), Scientific Data, 4, 170179 - 170179
Molecular and Functional Characterization of Disease-Propagating Stem Cells in Juvenile Myelomonocytic Leukemia
Louka E. et al, (2017), BLOOD, 130