Recent publications by Researchers affiliated with the Centre for Tropical Medicine and Global Health
Pharmacometric and statistical considerations for dose optimization
Chotsiri P. et al, (2024), CPT: Pharmacometrics & Systems Pharmacology
Population pharmacokinetic modelling of primaquine exposures in lactating women and breastfed infants
Wattanakul T. et al, (2024), Nature Communications, 15
Medication adherence framework: A population‐based pharmacokinetic approach and its application in antimalarial treatment assessments
Ding J. et al, (2024), CPT: Pharmacometrics & Systems Pharmacology
Efficacy of ultra-short, response-guided sofosbuvir and daclatasvir therapy for hepatitis C in a single-arm mechanistic pilot study
Flower B. et al, (2023), eLife, 12
Pharmacometric and Electrocardiographic Evaluation of Chloroquine and Azithromycin in Healthy Volunteers
Chotsiri P. et al, (2022), Clinical Pharmacology & Therapeutics, 112, 824 - 835
A pharmacometric approach to evaluate drugs for potential repurposing as COVID-19 therapeutics.
Wattanakul T. et al, (2022), Expert Rev Clin Pharmacol
Need for a Standardized Translational Drug Development Platform: Lessons Learned from the Repurposing of Drugs for COVID-19
Assmus F. et al, (2022), Microorganisms, 10, 1639 - 1639
Pre-clinical evaluation of antiviral activity of nitazoxanide against SARS-CoV-2
Driouich J-S. et al, (2022), eBioMedicine, 82, 104148 - 104148
Triple therapy with artemether–lumefantrine plus amodiaquine versus artemether–lumefantrine alone for artemisinin-resistant, uncomplicated falciparum malaria: an open-label, randomised, multicentre trial
Peto TJ. et al, (2022), The Lancet Infectious Diseases, 22, 867 - 878
Drug development for the treatment of onchocerciasis: Population pharmacokinetic and adverse events modeling of emodepside
Assmus F. et al, (2022), PLOS Neglected Tropical Diseases, 16, e0010219 - e0010219
Mechanistic Modeling of Primaquine Pharmacokinetics, Gametocytocidal Activity, and Mosquito Infectivity
Chotsiri P. et al, (2022), Clinical Pharmacology & Therapeutics, 111, 676 - 685
The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern
Abdelnabi R. et al, (2022), Nature Communications, 13
Development of weight and age-based dosing of daily primaquine for radical cure of vivax malaria
Taylor WR. et al, (2021), Malaria Journal, 20
Response to "Pharmacometric Approach to Evaluate Drug Dosing Adherence".
Ding J. et al, (2021), Clinical pharmacology and therapeutics, 110, 24 - 25
Development of Weight and Age-based Dosing of Daily Primaquine for Radical Cure of Vivax Malaria
Taylor WR. et al, (2021)
Pharmacokinetic Study of Rectal Artesunate in Children with Severe Malaria in Africa
Fanello C. et al, (2021), Antimicrobial Agents and Chemotherapy, 65
Semimechanistic Pharmacokinetic and Pharmacodynamic Modeling of Piperaquine in a Volunteer Infection Study with Plasmodium falciparum Blood-Stage Malaria
Wattanakul T. et al, (2021), Antimicrobial Agents and Chemotherapy, 65
Population Pharmacokinetic Properties of Antituberculosis Drugs in Vietnamese Children with Tuberculous Meningitis
Panjasawatwong N. et al, (2020), Antimicrobial Agents and Chemotherapy, 65
COVID-19 prevention and treatment: A critical analysis of chloroquine and hydroxychloroquine clinical pharmacology
White NJ. et al, (2020), PLOS Medicine, 17, e1003252 - e1003252