Recent publications by Researchers affiliated with the Centre for Tropical Medicine and Global Health
SEVUparin as a potential Adjunctive Treatment in children with severe malaria: A phase I trial safety and dose finding trial (SEVUSMAART)
Maitland K. et al, (2024), Wellcome Open Research, 8, 484 - 484
Hydroxyurea dose optimisation for children with sickle cell anaemia in sub-Saharan Africa (REACH): extended follow-up of a multicentre, open-label, phase 1/2 trial.
Aygun B. et al, (2024), The Lancet. Haematology, 11, e425 - e435
Nutritional supplementation in children with severe pneumonia in Uganda and Kenya (COAST-Nutrition): a phase 2 randomised controlled trial.
Kiguli S. et al, (2024), EClinicalMedicine, 72
A Phase I trial of Non-invasive Ventilation and seizure prophylaxis with levetiracetam In Children with Cerebral Malaria Trial (NOVICE-M Trial)
Maitland K. et al, (2024), Wellcome Open Research, 9, 281 - 281
Reducing transfusion utilization for children with sickle cell anemia in sub-Saharan Africa with hydroxyurea: Analysis from the phase I/II REACH trial.
Power-Hays A. et al, (2024), American journal of hematology
Impact of COVID-19 on mortality in coastal Kenya: a longitudinal open cohort study.
Otiende M. et al, (2023), Nature communications, 14
The Dantu blood group prevents parasite growth in vivo: Evidence from a controlled human malaria infection study.
Kariuki SN. et al, (2023), eLife, 12
Safety of age-dosed, single low-dose primaquine in children with glucose-6-phosphate dehydrogenase deficiency who are infected with Plasmodium falciparum in Uganda and the Democratic Republic of the Congo: a randomised, double-blind, placebo-controlled, non-inferiority trial
Taylor WR. et al, (2023), The Lancet Infectious Diseases, 23, 471 - 483
Mortality in rural coastal Kenya measured using the Kilifi Health and Demographic Surveillance System: a 16-year descriptive analysis
Otiende M. et al, (2023), Wellcome Open Research, 6, 327 - 327
Controlled human malaria infection (CHMI) outcomes in Kenyan adults is associated with prior history of malaria exposure and anti-schizont antibody response
Kapulu MC. et al, (2022), BMC Infectious Diseases, 22
Hydroxyurea is associated with lower malaria incidence in children with sickle cell anemia in sub-Saharan Africa.
Olupot-Olupot P. et al, (2022), Blood
Sickle cell anaemia and severe Plasmodium falciparum malaria: a secondary analysis of the Transfusion and Treatment of African Children Trial (TRACT)
Uyoga S. et al, (2022), The Lancet Child & Adolescent Health, 6, 606 - 613
Substantial misdiagnosis of severe malaria in African children
White NJ. et al, (2022), The Lancet, 400, 807 - 807
The significance of spleen size in children with sickle cell anemia.
Nardo-Marino A. et al, (2022), American journal of hematology
BIRC6 modifies risk of invasive bacterial infection in Kenyan children.
Gilchrist JJ. et al, (2022), eLife, 11
Improving the diagnosis of severe malaria in African children using platelet counts and plasma Pf HRP2 concentrations
Watson JA. et al, (2022), Science Translational Medicine, 14