Professor Ben Cooper
Contact information
Ben Cooper
Professor of Epidemiology
MAEMOD
Ben Cooper holds an MRC senior non-clinical research fellowship and is based in Oxford.
His work uses mathematical modelling and statistical techniques to help understand infectious disease dynamics and evaluate potential control measures. This involves developing mathematical models to help evaluate the likely impact and cost-effectiveness of control measures, developing and applying new statistical approaches based on mechanistic models for the analysis of longitudinal infectious disease data (increasingly making use of whole genome sequence data), and designing and analysing epidemiological studies. The major focus of this work is on antibiotic-resistant bacteria in resource-limited hospital settings.
Additional projects include within-host dynamics of Plasmodium vivax, ecological interactions of the nasopharyngeal flora, cost-effectiveness of seasonal influenza vaccination in Thailand, and dynamics and control of Hepatitis E infections in refugee camps.
Key publications
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Non-adherence in non-inferiority trials: pitfalls and recommendations.
Mo Y. et al, (2020), BMJ (Clinical research ed.), 370
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Quantifying antibiotic impact on within-patient dynamics of extended-spectrum beta-lactamase resistance.
Niehus R. et al, (2020), eLife, 9
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Transmission dynamics and control of multidrug-resistant Klebsiella pneumoniae in neonates in a developing country
Crellen T. et al, (2019), eLife, 8
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Decontamination Strategies and Bloodstream Infections With Antibiotic-Resistant Microorganisms in Ventilated Patients
Wittekamp BH. et al, (2018), JAMA, 320, 2087 - 2087
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Reactive and pre-emptive vaccination strategies to control hepatitis E infection in emergency and refugee settings: A modelling study.
Cooper BS. et al, (2018), PLoS neglected tropical diseases, 12
Recent publications
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Probabilistic transmission models incorporating sequencing data for healthcare-associated Clostridioides difficile outperform heuristic rules and identify strain-specific differences in transmission
Eyre DW. et al, (2021), PLOS Computational Biology, 17, e1008417 - e1008417
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Automating the Generation of Antimicrobial Resistance Surveillance Reports: Proof-of-Concept Study Involving Seven Hospitals in Seven Countries
Lim C. et al, (2020), Journal of Medical Internet Research, 22, e19762 - e19762
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Non-adherence in non-inferiority trials: pitfalls and recommendations.
Mo Y. et al, (2020), BMJ (Clinical research ed.), 370
-
Quantifying antibiotic impact on within-patient dynamics of extended-spectrum beta-lactamase resistance.
Niehus R. et al, (2020), eLife, 9
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Contact isolation versus standard precautions to decrease acquisition of extended-spectrum β-lactamase-producing Enterobacterales in non-critical care wards: a cluster-randomised crossover trial.
Maechler F. et al, (2020), The Lancet. Infectious Diseases, 20, 575 - 584