Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Dr Charles Sande

Dr Charles Sande

Contact information


CSande@kemri-wellcome.org

Podcast interview

Charles Sande explains how respiratory virus infections in early life can impact affected children later on

Social media

Charles Sande

Research scientist

My research focusses on pneumonia and other serious respiratory infections that affect infants and young children. Pneumonia remains a major killer, particularly in the developing world, where the healthcare infrastructure necessary for managing the most serious manifestations of the disease are inadequate. Our group is particularly interested in understanding the mechanisms of disease caused by respiratory infections such as respiratory syncytial virus (RSV) and Streptococcus pneumoniae. To gain a complete understanding of the mechanisms of disease pathology, we use a coordinated systems biology approach to examine in fine detail the interactions between the immune systems of sick children and the pathogens that cause pneumonia. We use a broad array of tools including mass spectrometry-based proteomics, protein microarrays, bacterial metagenomics and RNA-seq transcriptomics to understand host-pathogen interactions in the respiratory tract. Using these techniques we are gaining new insights into the breadth of the infant response to infection and how these responses may be leveraged in the development of effective interventions against pneumonia in the future.

Recent publications

More publications