Dr Claire Keene
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Research groups
Supervisors
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Claire Keene
DPhil Candidate
Education
MSc in International Health and Tropical Medicine (with distinction): University of Oxford, Nuffield Department of Clinical Medicine. Lincoln College (United Kingdom). 2016-2017
Thesis: Competing-risk approach to modelling length of stay in severe malaria patients in South-East Asia and the implications for planning of hospital services.
Diplomas in
- Public Health: Faculty of Public Health (United Kingdom). 2022
- Tropical Medicine and Hygiene: Royal College of Physicians (United Kingdom). 2017
- HIV Management: The Colleges of Medicine of South Africa (South Africa). 2016
MBBCh (with distinction): University of the Witwatersrand, Health Sciences Faculty (South Africa). 2007-2012
Previous Experience
Co-principal investigator then co-investigator for the AntiRetroviral Therapy In Second-line: investigating Tenofovir-lamivudine-dolutegravir (ARTIST) trial. Khayelitsha, South Africa. 2018 to present.
Welcome Service manager, HIV medical activities manager, then project medical referent (medical coordinator) for Médecins Sans Frontières Khayelitsha, South Africa. 2018 to 2020
Research assistant for the Oxford Health Systems Collaborative, University of Oxford. 2017 to 2018
Medical doctor for the South African Department of Health. 2013-2016.
Founder and co-owner of Study Doctor Tutoring. 2009-2019
Thesis
My thesis examines the engagement of people on antiretroviral therapy with HIV care in South Africa. Understanding how people engage with health services and their treatment over time is crucial to adapting service structure to respond to the changing needs of people in care. I am exploring engagement using group-based trajectory modelling applied to routine healthcare data from South Africa, in order to understand the patterns of how people engage with HIV care over time. This could help to direct the development of resource-efficient, differentiated services targeted at subgroups within the HIV positive population and their specific needs, as well as explore the applications of routine data in stratifying the people on antiretroviral treatment for intervention.
Recent publications
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Between empathy and anger: healthcare workers’ perspectives on patient disengagement from antiretroviral treatment in Khayelitsha, South Africa - a qualitative study
Nhemachena T. et al, (2023), BMC Primary Care, 24
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Conceptualising engagement with HIV care for people on treatment: the Indicators of HIV Care and AntiRetroviral Engagement (InCARE) Framework
Keene CM. et al, (2023), BMC Health Services Research, 23
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Standard-dose versus double-dose dolutegravir in HIV-associated tuberculosis in South Africa (RADIANT-TB): a phase 2, non-comparative, randomised controlled trial.
Griesel R. et al, (2023), The lancet. HIV
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Recycling tenofovir in second-line antiretroviral treatment with dolutegravir: outcomes and viral load trajectories to 72 weeks.
Keene CM. et al, (2023), J Acquir Immune Defic Syndr
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Initial supplementary dose of dolutegravir in second-line antiretroviral therapy: a non-comparative, double-blind, randomised placebo-controlled trial.
Zhao Y. et al, (2023), Clinical infectious diseases : an official publication of the Infectious Diseases Society of America