Professor Frank Smithuis

Contact information

Podcast Interview

Although malaria is decreasing in Myanmar, resistance to anti-malarials is on the rise in the region and the focus is now to treat people early, particularly in remote communities. MOCRU has set up a network of community health workers, trained and supplied with diagnostics, bednets and treatments, to help improve access to healthcare as well as produce the evidence to encourage policy changes.

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Research groups

Frank Smithuis

Associate Professor

Myanmar Oxford Clinical Research Unit

Frank Smithuis's interests include the epidemiology and management of malaria- in particular artemisinin resistant malaria- the aetiology and management of fever, and the management of tuberculosis, HIV and opportunistic infections.

The research unit is linked to a network of 6 clinics and 650 Community Health workers in remote areas. Most research questions originate from the day to day health issues in this network.

Effect of a single dose of primaquine on Plasmodium falciparum gametocyte carriage after ACT

Key publications

Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker
Tun KM. et al, (2015), The Lancet Infectious Diseases, 15, 415 - 421
Assessment of therapeutic responses to gametocytocidal drugs in Plasmodium falciparum malaria
White NJ. et al, (2014), Malaria Journal, 13
Mortality in Patients With AIDS-Related Cytomegalovirus Retinitis in Myanmar
Tun N. et al, (2014), Clinical Infectious Diseases, 59, 1650 - 1651
The effect of insecticide-treated bed nets on the incidence and prevalence of malaria in children in an area of unstable seasonal transmission in western Myanmar
Smithuis FM. et al, (2013), Malaria Journal, 12, 363 - 363
Entomological determinants of insecticide-treated bed net effectiveness in Western Myanmar
Smithuis FM. et al, (2013), Malaria Journal, 12, 364 - 364

Recent publications

Utility of Plasmodium falciparum DNA from rapid diagnostic test kits for molecular analysis and whole genome amplification.
Srisutham S. et al, (2020), Malaria journal, 19
Association of mutations in the Plasmodium falciparum Kelch13 gene (Pf3D7_1343700) with parasite clearance rates after artemisinin-based treatments—a WWARN individual patient data meta-analysis
(2019), BMC Medicine, 17
Competing risk events in antimalarial drug trials in uncomplicated Plasmodium falciparum malaria: a WorldWide Antimalarial Resistance Network individual participant data meta-analysis
(2019), Malaria Journal, 18
TELEMENTORING WITH PROJECT ECHO, A PILOT PROJECT IN MYANMAR
Tun NN. et al, (2019), TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 113, S69 - S70
Plasmodium vivax Relapse Rates Following Plasmodium falciparum Malaria Reflect Previous Transmission Intensity.
Ashley EA. et al, (2019), The Journal of infectious diseases, 220, 100 - 104

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