Contact information
Research groups
Lucie Kafkova
Project Manager, IDDO
Lucie manages the Neglected Tropical Disease project portfolio at IDDO.
Before joining IDDO, Lucie studied molecular biology of membrane proteases as a Marie Curie Postdoctoral Fellow at the Sir William Dunn School of Pathology. Prior, she earned a PhD in Microbiology and Immunology from the University at Buffalo for her work on molecular biology of African Trypanosomes.
Team: IDDO
Address:
Big Data Institute
University of Oxford
Li Ka Shing Centre for Health Information and Discovery
Old Road Campus
Oxford OX3 7LF
UK
Recent publications
Mechanism-based traps enable protease and hydrolase substrate discovery
Journal article
Tang S. et al, (2022), Nature, 602, 701 - 707
Structural Basis of Protein Arginine Methyltransferase Activation by a Catalytically Dead Homolog (Prozyme)
Journal article
Hashimoto H. et al, (2020), Journal of Molecular Biology, 432, 410 - 426
Trypanosoma brucei PRMT1 Is a Nucleic Acid Binding Protein with a Role in Energy Metabolism and the Starvation Stress Response
Journal article
Kafková L. et al, (2018), mBio, 9
The Major Protein Arginine Methyltransferase in Trypanosoma brucei Functions as an Enzyme-Prozyme Complex
Journal article
Kafková L. et al, (2017), Journal of Biological Chemistry, 292, 2089 - 2100
Integrity of the core mitochondrial RNA-binding complex 1 is vital for trypanosome RNA editing
Journal article
Huang Z. et al, (2015), RNA, 21, 2088 - 2102