Dr Makoto Saito
Research groups
Makoto Saito
Senior Medical Epidemiologist
- Head of AMR disease theme, Infectious Diseases Data Observatory (IDDO)
I am an infectious disease physician by training and a clinical epidemiologist based at the Infectious Diseases Data Observatory (IDDO).
Over the past few years, I have dedicated my work to studying the epidemiology of malaria in pregnancy, focusing particularly on the use of antimalarials during pregnancy. My doctoral project (2015-2019, St Edmund Hall, Clarendon scholar) aimed to summarize the available evidence to optimize the clinical care of pregnant women with malaria and improve the quality of research methodology for the future. Since then, I have closely collaborated with researchers at the Shoklo Malaria Research Unit (SMRU, Mae Sot, Thailand) and the WorldWide Antimalarial Resistance Network (WWARN, Oxford).
My research interests extend broadly to the epidemiology of clinical infectious diseases, with a particular focus on malaria and other tropical infectious diseases, as well as nosocomial bacterial infections and antimicrobial resistance (AMR).
Key publications
Severe falciparum malaria in pregnancy in Southeast Asia: a multi-centre retrospective cohort study
Journal article
Saito M. et al, (2023), BMC Medicine, 21
Pregnancy outcomes after first-trimester treatment with artemisinin derivatives versus non-artemisinin antimalarials: a systematic review and individual patient data meta-analysis
Journal article
Saito M. et al, (2023), The Lancet, 401, 118 - 130
A randomized controlled trial of dihydroartemisinin-piperaquine, artesunate-mefloquine and extended artemether-lumefantrine treatments for malaria in pregnancy on the Thailand-Myanmar border
Journal article
Saito M. et al, (2021), BMC Medicine, 19
Pregnancy outcomes and risk of placental malaria after artemisinin-based and quinine-based treatment for uncomplicated falciparum malaria in pregnancy: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis
Journal article
Saito M. et al, (2020), BMC Medicine, 18
Efficacy and tolerability of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: a systematic review and individual patient data meta-analysis
Journal article
Saito M. et al, (2020), The Lancet Infectious Diseases, 20, 943 - 952
Recent publications
Transplacental Transfer of Lumefantrine, Mefloquine, and Piperaquine: A Comparison of Concentrations in Mothers, Neonates, and Cord Blood
Journal article
Saito M. et al, (2026), Clinical Infectious Diseases, 82, e165 - e173
Epidemiological Shifts in Visceral Leishmaniasis Incidence, Relapse, and Mortality in Brazil, 2007–2023: Analysis Using the National Notifiable Diseases Information System
Journal article
Assefa DG. et al, (2026), Open Forum Infectious Diseases, 13
Invasive mold infection in heart transplant recipients: A nationwide multicenter matched case–control study between 2008 and 2022 in France
Journal article
Hoellinger B. et al, (2026), American Journal of Transplantation
Tafenoquine lactation pharmacokinetics: a pilot study
Journal article
Gilder ME. et al, (2025), Malaria Journal, 25
Determinants of the use of insecticide-treated nets and intermittent preventive treatment of malaria among pregnant women in Angola
Journal article
Aoki A. et al, (2025), International Health, 17, 934 - 941