Dr Makoto Saito
Contact information
Research groups
Makoto Saito
Medical Epidemiologist, Infectious Diseases Data Observatory
I am an infectious disease physician by training and a clinical epidemiologist based at the Infectious Diseases Data Observatory (IDDO).
Over the past few years, I have dedicated my work to studying the epidemiology of malaria in pregnancy, focusing particularly on the use of antimalarials during pregnancy. My doctoral project (2015-2019, St Edmund Hall, Clarendon scholar) aimed to summarize the available evidence to optimize the clinical care of pregnant women with malaria and improve the quality of research methodology for the future. Since then, I have closely collaborated with researchers at the Shoklo Malaria Research Unit (SMRU, Mae Sot, Thailand) and the WorldWide Antimalarial Resistance Network (WWARN, Oxford).
My research interests extend broadly to the epidemiology of clinical infectious diseases, with a particular focus on malaria and other tropical infectious diseases, as well as nosocomial bacterial infections and antimicrobial resistance (AMR).
Key publications
-
Pregnancy outcomes after first-trimester treatment with artemisinin derivatives versus non-artemisinin antimalarials: a systematic review and individual patient data meta-analysis.
Saito M. et al, (2023), Lancet (London, England), 401, 118 - 130
-
Efficacy and tolerability of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: a systematic review and individual patient data meta-analysis
Saito M. et al, (2020), The Lancet Infectious Diseases, 20, 943 - 952
-
Pregnancy outcomes and risk of placental malaria after artemisinin-based and quinine-based treatment for uncomplicated falciparum malaria in pregnancy: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis
Saito M. et al, (2020), BMC Medicine, 18
-
A randomized controlled trial of dihydroartemisinin-piperaquine, artesunate-mefloquine and extended artemether-lumefantrine treatments for malaria in pregnancy on the Thailand-Myanmar border
Saito M. et al, (2021), BMC Medicine, 19
-
Severe falciparum malaria in pregnancy in Southeast Asia: a multi-centre retrospective cohort study.
Saito M. et al, (2023), BMC medicine, 21
Recent publications
-
Clinical impact of the use of chronic suppressive antibiotics against recurrent ventricular assist device infections.
Yamamoto S. et al, (2024), Microbiol Spectr
-
Hepatitis B Virus Reactivation after Switch to Cabotegravir/Rilpivirine in Patient with Low Hepatitis B Surface Antibody.
Adachi E. et al, (2024), Emerging infectious diseases, 30, 1668 - 1671
-
Comparison of lumefantrine, mefloquine, and piperaquine concentrations between capillary plasma and venous plasma samples in pregnant women with uncomplicated falciparum and vivax malaria
Saito M. et al, (2024), Antimicrobial Agents and Chemotherapy, 68
-
Characterization of mutations in hepatitis B virus DNA isolated from Japanese HBsAg-positive blood donors in 2021 and 2022.
Sedohara A. et al, (2024), Archives of virology, 169
-
Favorable Virological Outcome, Characteristics of Injection Site Reactions, Decrease in Renal Function Biomarkers in Asian People with HIV Receiving Long-Acting Cabotegravir Plus Rilpivirine.
Adachi E. et al, (2024), AIDS Res Hum Retroviruses, 40, 216 - 222